HIV molecular immunology database
Found 25 matching records:
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*02) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | Intracellular cytokine staining, Other | |
Keywords | rate of progression, escape, mutation acquisition |
Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(221-) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*02:01) | |
Immunogen | vaccine | |
Country | Botswana, United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | vaccine antigen design |
Vaccine type | DNA, polyepitope |
---|---|
Vaccine strain | multiple epitope immunogen |
Gorse2008a Geoffrey J. Gorse, Lindsey R. Baden, Margaret Wecker, Mark J. Newman, Guido Ferrari, Kent J. Weinhold, Brian D. Livingston, Tonya L. Villafana, Hongli Li, Elizabeth Noonan, Nina D. Russell, and HIV Vaccine Trials Network. Safety and Immunogenicity of Cytotoxic T-Lymphocyte Poly-Epitope, DNA Plasmid (EP HIV-1090) Vaccine in Healthy, Human Immunodeficiency Virus Type 1 (HIV-1)-Uninfected Adults. Vaccine, 26(2):215-223, 10 Jan 2008. PubMed ID: 18055072. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*02:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other | |
Keywords | vaccine-induced immune responses, HLA cross-presentation, HLA associated polymorphism |
Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145 DU422) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*02:01) | |
Immunogen | in vitro stimulation or selection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding | |
Keywords | dendritic cells |
Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(139-147 HXB3) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | mouse(A*02:01) | |
Immunogen | vaccine | |
Experimental methods | ||
Keywords | binding affinity, computational epitope prediction |
Vaccine type | DNA, peptide |
---|---|
Vaccine strain | B clade HXB3 |
Vaccine component | Nef |
Adjuvant | Complete Freund's Adjuvant (CFA) |
Sandberg2000 J. K. Sandberg, A. C. Leandersson, C. Devito, B. Kohleisen, V. Erfle, A. Achour, M. Levi, S. Schwartz, K. Karre, B. Wahren, and J. Hinkula. Human immunodeficiency virus type 1 Nef epitopes recognized in HLA-A2 transgenic mice in response to DNA and peptide immunization. Virology, 273(1):112-9, 20 Jul 2000. PubMed ID: 10891413. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | Nef221 | |
Subtype | B | |
Species (MHC/HLA) | human(A2) | |
Immunogen | vaccine | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | vaccine antigen design |
Vaccine type | DNA, polyepitope |
---|---|
Vaccine component | other |
Wilson2008 Cara C. Wilson, Mark J. Newman, Brian D. Livingston, Samantha MaWhinney, Jeri E. Forster, Jim Scott, Robert T. Schooley, and Constance A. Benson. Clinical Phase 1 Testing of the Safety and Immunogenicity of an Epitope-Based DNA Vaccine in Human Immunodeficiency Virus Type 1-Infected Subjects Receiving Highly Active Antiretroviral Therapy. Clin. Vaccine Immunol., 15(6):986-994, Jun 2008. PubMed ID: 18400976. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | Nef137 | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay | |
Keywords | binding affinity, subtype comparisons, computational epitope prediction |
Corbet2003 Sylvie Corbet, Henrik Vedel Nielsen, Lasse Vinner, Sanne Lauemoller, Dominic Therrien, Sheila Tang, Gitte Kronborg, Lars Mathiesen, Paul Chaplin, Søren Brunak, Søren Buus, and Anders Fomsgaard. Optimization and Immune Recognition of Multiple Novel Conserved HLA-A2, Human Immunodeficiency Virus Type 1-Specific CTL Epitopes. J. Gen. Virol., 84(Pt 9):2409-2421, Sep 2003. PubMed ID: 12917462. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | Nef137-145 | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | responses in children, immunodominance, characterizing CD8+ T cells |
Chandwani2004 R. Chandwani, K. A. Jordan, B. L. Shacklett, E. Papasavvas, L. J. Montaner, M. G. Rosenberg, D. F. Nixon, and J. K. Sandberg. Limited Magnitude and Breadth in the HLA-A2-Restricted CD8 T-Cell Response to Nef in Children with Vertically Acquired HIV-1 Infection. Scand. J. Immunol., 59(1):109-114, Jan 2004. PubMed ID: 14723629. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | ||
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | rate of progression, immunodominance |
Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(A*23) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(A*25) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(158-166) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(A2 supertype) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | supertype, rate of progression |
Propato2001 A. Propato, E. Schiaffella, E. Vicenzi, V. Francavilla, L. Baloni, M. Paroli, L. Finocchi, N. Tanigaki, S. Ghezzi, R. Ferrara, R. Chesnut, B. Livingston, A. Sette, R. Paganelli, F. Aiuti, G. Poli, and V. Barnaba. Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity. Hum. Immunol., 62(6):561-76, Jun 2001. PubMed ID: 11390031. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | Nef221 | |
Subtype | A, B, C | |
Species (MHC/HLA) | human, mouse(A2 supertype) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | binding affinity, supertype, vaccine-induced immune responses, HLA cross-presentation |
Wilson2003 Cara C. Wilson, Denise McKinney, Michelle Anders, Samantha MaWhinney, Jeri Forster, Claire Crimi, Scott Southwood, Alessandro Sette, Robert Chesnut, Mark J Newman, and Brian D Livingston. Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1. J. Immunol., 171(10):5611-5623, 15 Nov 2003. PubMed ID: 14607970. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(A*32) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(A*80) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Subtype | B, C | |
Species (MHC/HLA) | human(B*15:17, B57) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*36, A*66, B*15:17, B*53, C*04, C*06; A*02, A*23, B*35, B*57, C*04, C*07 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HLA cross-presentation, optimal epitope, novel epitope |
Frahm2005a Nicole Frahm, Sharon Adams, Photini Kiepiela, Caitlyn H. Linde, Hannah S. Hewitt, Mathias Lichterfeld, Kaori Sango, Nancy V. Brown, Eunice Pae, Alysse G. Wurcel, Marcus Altfeld, Margaret E. Feeney, Todd M. Allen, Timothy Roach, M. Anne St. John, Eric S. Daar, Eric Rosenberg, Bette Korber, Francesco Marincola, Bruce D. Walker, Philip J. R. Goulder, and Christian Brander. HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load. J. Virol., 79(16):10218-10225, Aug 2005. PubMed ID: 16051815. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(B*15:40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | ||
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*57) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression |
Streeck2014 Hendrik Streeck, Richard Lu, Noor Beckwith, Mark Milazzo, Michelle Liu, Jean-Pierre Routy, Susan Little, Heiko Jessen, Anthony D. Kelleher, Frederick Hecht, Rafick-Pierre Sekaly, Galit Alter, David Heckerman, Mary Carrington, Eric S. Rosenberg, and Marcus Altfeld. Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome. J. Virol., 88(21):12793-12801, Nov 2014. PubMed ID: 25165102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | ||
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*63) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Species (MHC/HLA) | human(C*14) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | LTNP/EC-4: A*03, A*11, B*35, B*51, C*04, C*15; LTNP/EC-13: A*03, A*24, B*15, B*44, C*07, C*14 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, immunodominance |
Migueles2015 Stephen A. Migueles, Daniel Mendoza, Matthew G. Zimmerman, Kelly M. Martins, Sushila A. Toulmin, Elizabeth P. Kelly, Bennett A. Peterson, Sarah A. Johnson, Eric Galson, Kate O. Poropatich, Andy Patamawenu, Hiromi Imamichi, Alexander Ober, Catherine A. Rehm, Sara Jones, Claire W. Hallahan, Dean A. Follmann, and Mark Connors. CD8+ T-Cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types. EBioMedicine, 2(1):46-58, Jan 2015. PubMed ID: 26137533. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Subtype | B, C | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Country | Sweden | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | subtype comparisons, computational epitope prediction, vaccine antigen design |
Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(137-145) DNA(9205..9231) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(137-145) | |
Epitope |
LTFGWCFKL
|
Epitope Alignment
|
Epitope Name | LL9 | |
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | AC1: A*02:01, A*30:01, B*37:01, B*38:01, C*06:02, C*12:03; VP1: A*02:01, A*03:01, B*41:01, B*52:01, C*03:03, C*17:01 | |
Country | United States | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | NK cells, transmission pair |
Walker-Sperling2017 Victoria E. Walker-Sperling, Christopher W. Pohlmeyer, Rebecca T. Veenhuis, Megan May, Krystle A. Luna, Allison R. Kirkpatrick, Oliver Laeyendecker, Andrea L. Cox, Mary Carrington, Justin R. Bailey, Roberto C. Arduino, and Joel N. Blankson. Factors Associated with the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller. EBioMedicine, 16:141-149, Feb 2017. PubMed ID: 28159573. Show all entries for this paper.