HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 52195

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2002 Rupert Kaul, Sarah L. Rowland-Jones, Geraldine Gillespie, Joshua Kimani, Tao Dong, Peter Kiama, J. Neil Simonsen, Job J. Bwayo, Andrew J. McMichael, and Francis A. Plummer. Gonococcal Cervicitis is Associated with Reduced Systemic CD8+ T Cell Responses in Human Immunodeficiency Virus Type 1-Infected and Exposed, Uninfected Sex Workers. J. Infect. Dis., 185(10):1525-1529, 15 May 2002. PubMed ID: 11992292. Show all entries for this paper.


Displaying record number 53816

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location Gag(147-155)
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Country Canada
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords  

Notes

References

Mason2005 R. D. Mason, M. I. Bowmer, C. M. Howley, and M. D. Grant. Cross-Reactive Cytotoxic T Lymphocytes against Human Immunodeficiency Virus Type 1 Protease and Gamma Interferon-Inducible Protein 30. J. Virol., 79(9):5529-5536, May 2005. PubMed ID: 15827167. Show all entries for this paper.


Displaying record number 145

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24( subtype A)
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Subtype A
Species (MHC/HLA) human(B57, B58)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords  

Notes

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.


Displaying record number 1694

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24(147-155)
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Species (MHC/HLA) human(B57, B58)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS), immunodominance

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 55052

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location Gag
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Species (MHC/HLA) human(B*57:03)
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords subtype comparisons, HLA cross-presentation, variant cross-reactivity

Notes

References

Currier2006 Jeffrey R. Currier, Unchalee Visawapoka, Sodsai Tovanabutra, Carl J. Mason, Deborah L. Birx, Francine E. McCutchan, and Josephine H. Cox. CTL Epitope Distribution Patterns in the Gag and Nef Proteins of HIV-1 from Subtype A Infected Subjects in Kenya: Use of Multiple Peptide Sets Increases the Detectable Breadth of the CTL Response. BMC Immunol, 7:8, 2006. PubMed ID: 16620386. Show all entries for this paper.


Displaying record number 53892

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24(15-23)
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Subtype C
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Country India
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, immunodominance

Notes

References

Thakar2005 Madhuri R. Thakar, Leena S. Bhonge, Samir K. Lakhashe, U. Shankarkumar, Suvarna S. Sane, Smita S. Kulkarni, Bharati A. Mahajan, and Ramesh S. Paranjape. Cytolytic T Lymphocytes (CTLs) from HIV-1 Subtype C-Infected Indian Patients Recognize CTL Epitopes From a Conserved Immunodominant Region of HIV-1 Gag and Nef. J. Infect. Dis., 192(5):749-759, 1 Sep 2005. PubMed ID: 16088824. Show all entries for this paper.


Displaying record number 1333

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HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location  
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001 R. Kaul, S. L. Rowland-Jones, J. Kimani, T. Dong, H. B. Yang, P. Kiama, T. Rostron, E. Njagi, J. J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Late Seroconversion in HIV-Resistant Nairobi Prostitutes Despite Pre-Existing HIV-Specific CD8+ Responses. J. Clin. Invest., 107(3):341-349, Feb 2001. URL: http://www.jci.org/cgi/content/full/107/3/341. PubMed ID: 11160158. Show all entries for this paper.


Displaying record number 58442

Download this epitope record as JSON.

HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24(15-23)
Epitope LSPRTLNAW Epitope Alignment
LSPRTLNAW epitope logo
Subtype A1
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Proliferation
Keywords assay or method development, vaccine antigen design, characterizing CD8+ T cells

Notes

References

Richmond2011 Meika Richmond, Lyle R. McKinnon, Sandra A. Koesters Kiazyk, Charles Wachihi, Makobu Kimani, Joshua Kimani, Francis A. Plummer, and T. Blake Ball. Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function. J. Virol., 85(3):1275-1286, Feb 2011. PubMed ID: 21084478. Show all entries for this paper.


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