HIV molecular immunology database
Found 1 matching record:
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|gp160 Epitope Map|
|Author Location||gp120(410-429 H3DCG)|
Siliciano1988 R. Siliciano, T. Lawton, C. Knall, R. Karr, P. Berman, T. Gregory, and E. Reinherz. Analysis of Host-Virus Interactions in AIDS with Anti-gp120 T Cell Clones: Effect of HIV Sequence Variation and a Mechanism for CD4+ Cell Depletion. Cell, 54:561-575, 1988. This article demonstrated that a class II HLA-DR4 restricted response can be stimulated by CD4 uptake of gp120, suggesting a mechanism for T-cell depletion in vivo. This peptide containing the epitope was also able to stimulate a class I restricted, CD8+ CTL response. PubMed ID: 2969774. Show all entries for this paper.