HIV molecular immunology database


Search CTL/CD8+ T-Cell Epitope Database

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Displaying record number 281

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HXB2 Location Gag(263-272)
Gag Epitope Map
Author Location p24(263-272)
Epitope KRWIIMGNK Epitope Alignment
KRWIIMGNK epitope logo
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Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords escape



Nowak1995 M. A. Nowak, R. M. May, R. E. Phillips, S. Rowland-Jones, D. G. Lalloo, S. McAdam, P. Klenerman, B. Koppe, K. Sigmund, C. R. M. Bangham, and A. J. McMichael. Antigenic Oscillations and Shifting Immunodominance in HIV-1 Infections. Nature, 375:606-611, 1995. This paper presents longitudinal studies of epitope variation and corresponding CTL responses in two patients. A mathematical model was created to provide a framework to explain the observed shifts in epitope and CTLp frequencies. For discussion, see also: J. M. Coffin, Nature 375:534-535 (1995). PubMed ID: 7791879. Show all entries for this paper.

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