HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 57297

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HXB2 Location Gag(263-274)
p24(131-142)
DNA(1576..1611)
Gag Epitope Map
Author Location p24(131-142)
Epitope KRWIILGLNKIV Epitope Alignment
KRWIILGLNKIV epitope logo
Epitope Name KV12
Subtype B
Species (MHC/HLA) human(B*27)
Immunogen peptide-HLA interaction
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other
Keywords epitope processing

Notes

References

Tenzer2009 Stefan Tenzer, Edmund Wee, Anne Burgevin, Guillaume Stewart-Jones, Lone Friis, Kasper Lamberth, Chih-hao Chang, Mikkel Harndahl, Mirjana Weimershaus, Jan Gerstoft, Nadja Akkad, Paul Klenerman, Lars Fugger, E. Yvonne Jones, Andrew J. McMichael, Søren Buus, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. Antigen Processing Influences HIV-Specific Cytotoxic T Lymphocyte Immunodominance. Nat. Immunol., 10(6):636-646, Jun 2009. PubMed ID: 19412183. Show all entries for this paper.


Displaying record number 288

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HXB2 Location Gag(263-274)
p24(131-142)
DNA(1576..1611)
Gag Epitope Map
Author Location p24(265-276)
Epitope KRWIILGLNKIV Epitope Alignment
KRWIILGLNKIV epitope logo
Species (MHC/HLA) human(B27)
Immunogen peptide-HLA interaction
Experimental methods  
Keywords  

Notes

References

Jardetzky1991 T. S. Jardetzky, W. S. Lane, R. A. Robinson, D. R. Madden, and D. C. Wiley. Identification of Self Peptides Bound to Purified HLA-B27. Nature, 353:326-329, 1991. A pool of endogenous peptides bound to the human class I MHC molecule, HLA-B27, has been isolated. Microsequence analysis of the pool and of 11 HPLC-purified peptides provides information on the binding specificity of the HLA-B27 molecule. The peptides all seem to be nonamers, seven of which match to protein sequences in a database search. These self peptides derive from abundant cytosolic or nuclear proteins, such as histone, ribosomal proteins, and members of the 90K heat-shock protein family. PubMed ID: 1922338. Show all entries for this paper.


Displaying record number 289

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HXB2 Location Gag(263-274)
p24(131-142)
DNA(1576..1611)
Gag Epitope Map
Author Location p24(263-274 LAI)
Epitope KRWIILGLNKIV Epitope Alignment
KRWIILGLNKIV epitope logo
Subtype B
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords dendritic cells

Notes

References

Fan1997 Z. Fan, X. L. Huang, L. Zheng, C. Wilson, L. Borowski, J. Liebmann, P. Gupta, J. Margolick, and C. Rinaldo. Cultured Blood Dendritic Cells Retain HIV-1 Antigen-Presenting Capacity for Memory CTL During Progressive HIV-1 Infection. J. Immunol., 159:4973-4982, 1997. PubMed ID: 9366424. Show all entries for this paper.


Displaying record number 1454

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HXB2 Location Gag(263-274)
p24(131-142)
DNA(1576..1611)
Gag Epitope Map
Author Location p24(131-142)
Epitope KRWIILGLNKIV Epitope Alignment
KRWIILGLNKIV epitope logo
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 60662

Download this epitope record as JSON.

HXB2 Location Gag(263-274)
p24(131-142)
DNA(1576..1611)
Gag Epitope Map
Author Location p24(131-142)
Epitope KRWIILGLNKIV Epitope Alignment
KRWIILGLNKIV epitope logo
Epitope Name KV-12
Subtype B, C
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


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