HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 54567

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HXB2 Location Pol(101-110)
Protease(45-54)
DNA(2385..2414)
Pol Epitope Map
Author Location Protease(45-54)
Epitope KMIGGIGGFI Epitope Alignment
KMIGGIGGFI epitope logo
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country United States
Experimental methods Intracellular cytokine staining, Other
Keywords rate of progression, escape, mutation acquisition

Notes

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


Displaying record number 53441

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HXB2 Location Pol(101-110)
Protease(45-54)
DNA(2385..2414)
Pol Epitope Map
Author Location Pol(45-54 IIIB)
Epitope KMIGGIGGFI Epitope Alignment
KMIGGIGGFI epitope logo
Show epitope variants
Epitope Name pol45-54
Subtype B
Species (MHC/HLA) humanized mouse(A*02:01)
Immunogen vaccine
Experimental methods Intracellular cytokine staining
Keywords epitope processing, vaccine-induced immune responses, immunodominance, variant cross-reactivity, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine strain B clade IIIB
Vaccine component Gag-Pol

Notes

References

Singh2004 Rana A K Singh and Michael A Barry. Repertoire and Immunofocusing of CD8 T Cell Responses Generated by HIV-1 gag-pol and Expression Library Immunization Vaccines. J. Immunol., 173(7):4387-4393, 1 Oct 2004. PubMed ID: 15383568. Show all entries for this paper.


Displaying record number 54657

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HXB2 Location Pol(101-110)
Protease(45-54)
DNA(2385..2414)
Pol Epitope Map
Author Location Protease(45-54 HXB2)
Epitope KMIGGIGGFI Epitope Alignment
KMIGGIGGFI epitope logo
Show epitope variants
Epitope Name KI10
Subtype B
Species (MHC/HLA) human(A2, B62)
Immunogen HIV-1 infection
Country Germany
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, HLA associated polymorphism, drug resistance

Notes

References

Mueller2007 Sandra M. Mueller, Birgit Schaetz, Kathrin Eismann, Silke Bergmann, Michael Bauerle, Matthias Schmitt-Haendle, Hauke Walter, Barbara Schmidt, Klaus Korn, Heinrich Sticht, Bernd Spriewald, Ellen G. Harrer, and Thomas Harrer. Dual Selection Pressure by Drugs and HLA Class I-Restricted Immune Responses on Human Immunodeficiency Virus Type 1 Protease. J. Virol., 81(6):2887-2898, Mar 2007. PubMed ID: 17202219. Show all entries for this paper.


Displaying record number 1594

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HXB2 Location Pol(101-110)
Protease(45-54)
DNA(2385..2414)
Pol Epitope Map
Author Location Pol(125-134)
Epitope KMIGGIGGFI Epitope Alignment
KMIGGIGGFI epitope logo
Species (MHC/HLA) human(A2 supertype)
Immunogen HIV-1 infection
Experimental methods  
Keywords supertype, rate of progression

Notes

References

Propato2001 A. Propato, E. Schiaffella, E. Vicenzi, V. Francavilla, L. Baloni, M. Paroli, L. Finocchi, N. Tanigaki, S. Ghezzi, R. Ferrara, R. Chesnut, B. Livingston, A. Sette, R. Paganelli, F. Aiuti, G. Poli, and V. Barnaba. Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity. Hum. Immunol., 62(6):561-76, Jun 2001. PubMed ID: 11390031. Show all entries for this paper.


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