HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 49 matching records:

Displaying record number 57411

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(20-29)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection, in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 59129

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 NL4.3)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infected monocyte-derived, HIV-1 infection
Country United States
Experimental methods Chromium-release assay, Other
Keywords epitope processing, dendritic cells

Notes

References

Dinter2014 Jens Dinter, Pauline Gourdain, Nicole Y. Lai, Ellen Duong, Edith Bracho-Sanchez, Marijana Rucevic, Paul H. Liebesny, Yang Xu, Mariko Shimada, Musie Ghebremichael, Daniel G. Kavanagh, and Sylvie Le Gall. Different Antigen-Processing Activities in Dendritic Cells, Macrophages, and Monocytes Lead to Uneven Production of HIV Epitopes and Affect CTL Recognition. J. Immunol., 193(9):4322-4334, 1 Nov 2014. PubMed ID: 25230751. Show all entries for this paper.


Displaying record number 1773

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression, acute/early infection

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 53838

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Epitope Name KR9
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Patient MHC/HLA A*03, A*31, B*08, B*15, Cw*04, Cw*07; M-1001: A*03, A*31, B*08, B*15, Cw*04, Cw*07; P-1024: A*24, A*31, B*15, B*47, Cw*04, Cw*07
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords responses in children, mother-to-infant transmission, escape, acute/early infection, viral fitness and reversion

Notes

References

Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.


Displaying record number 59916

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54752

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*03)
Immunogen peptide-HLA interaction
Experimental methods Tetramer binding
Keywords binding affinity

Notes

References

Gillespie2007 Geraldine M. A. Gillespie, Arman Bashirova, Tao Dong, Daniel W. McVicar, Sarah L. Rowland-Jones, and Mary Carrington. Lack of KIR3DS1 Binding to MHC Class I Bw4 Tetramers in Complex with CD8+ T Cell Epitopes. AIDS Res. Hum. Retroviruses, 23(3):451-455, Mar 2007. PubMed ID: 17411378. Show all entries for this paper.


Displaying record number 1259

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 SF2)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Altfeld2001c M. Altfeld, M. M. Addo, R. L. Eldridge, X. G. Yu, S. Thomas, A. Khatri, D. Strick, M. N. Phillips, G. B. Cohen, S. A. Islam, S. A. Kalams, C. Brander, P. J. Goulder, E. S. Rosenberg, B. D. Walker, and The HIV Study Collaboration.. Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol., 167(5):2743-52, 1 Sep 2001. URL: http://www.jimmunol.org/cgi/content/full/167/5/2743. PubMed ID: 11509618. Show all entries for this paper.


Displaying record number 53818

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Subtype A
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Patient MHC/HLA A*0101, A*0301, B*0801; A*0201, A*3101, B*3501, B*3905
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords escape, acute/early infection, variant cross-reactivity

Notes

References

Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.


Displaying record number 53022

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, CD8 T-cell Elispot granzyme B
Keywords Th1, characterizing CD8+ T cells

Notes

References

Kleen2004 Thomas O. Kleen, Robert Asaad, Samuel J. Landry, Bernhard O. Boehm, and Magdalena Tary-Lehmann. Tc1 Effector Diversity Shows Dissociated Expression of Granzyme B and Interferon-gamma in HIV Infection. AIDS, 18(3):383-392, 20 Feb 2004. PubMed ID: 15090789. Show all entries for this paper.


Displaying record number 7

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*0301)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61186

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 1111

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location  
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods  
Keywords acute/early infection

Notes

References

Wilson2000 J. D. Wilson, G. S. Ogg, R. L. Allen, C. Davis, S. Shaunak, J. Downie, W. Dyer, C. Workman, S. Sullivan, A. J. McMichael, and S. L. Rowland-Jones. Direct Visualization of HIV-1-Specific Cytotoxic T Lymphocytes During Primary Infection. AIDS, 14:225-233, 2000. PubMed ID: 10716497. Show all entries for this paper.


Displaying record number 57067

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 DU422)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A*0301)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 1444

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A*0301, A3, B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 54831

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag( Henan isolate)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Gong2006 Xiaoyan Gong, Xien Gui, Yuxia Zhang, and Po Tien. Screening for CD8 Cytotoxic T Lymphocytes Specific for Gag of Human Immunodeficiency Virus Type 1 Subtype B' Henan Isolate from China and Identification of Novel Epitopes Restricted by the HLA-A2 and HLA-A11 Alleles. J. Gen. Virol., 87(Pt 1):151-158, Jan 2006. PubMed ID: 16361427. Show all entries for this paper.


Displaying record number 53201

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 B consensus)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords epitope processing, immunodominance, escape, acute/early infection, characterizing CD8+ T cells, viral fitness and reversion

Notes

References

Allen2004 Todd M Allen, Marcus Altfeld, Xu G. Yu, Kristin M. O'Sullivan, Mathias Lichterfeld, Sylvie Le Gall, Mina John, Bianca R. Mothe, Paul K. Lee, Elizabeth T. Kalife, Daniel E. Cohen, Kenneth A. Freedberg, Daryld A. Strick, Mary N. Johnston, Alessandro Sette, Eric S. Rosenberg, Simon A. Mallal, Philip J. R. Goulder, Christian Brander, and Bruce D. Walker. Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(13):7069-7078, Jul 2004. PubMed ID: 15194783. Show all entries for this paper.


Displaying record number 53217

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords review, epitope processing, escape

Notes

References

Goulder2004 Philip J R Goulder and David I Watkins. HIV and SIV CTL Escape: Implications for Vaccine Design. Nat. Rev. Immunol., 4(8):630-640, Aug 2004. PubMed ID: 15286729. Show all entries for this paper.


Displaying record number 53379

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location ( B consensus)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B14, B60, Cw3, Cw7
Country United States
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 53393

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 exposed seronegative
Patient MHC/HLA A1, A3, B39, B44, Cw4, Cw6
Experimental methods T-cell Elispot
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Missale2004 Gabriele Missale, Laura Papagno, Amalia Penna, Massimo Pilli, Alessandro Zerbini, Piero Vitali, Giovanni Pieroni, Simona Urbani, Jacopo Uggeri, Susana Pinheiro, Sarah Rowland-Jones, and Carlo Ferrari. Parenteral Exposure to High HIV Viremia Leads to Virus-Specific T Cell Priming without Evidence of Infection. Eur. J. Immunol., 34(11):3208-3215, Nov 2004. PubMed ID: 15459901. Show all entries for this paper.


Displaying record number 53546

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A3, B57, B7, Cw6, Cw7
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 53779

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p24
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) (A3)
Immunogen  
Experimental methods  
Keywords review, immunodominance, acute/early infection, kinetics

Notes

References

Lichterfeld2005 Mathias Lichterfeld, Xu G. Yu, Sylvie Le Gall, and Marcus Altfeld. Immunodominance of HIV-1-Specific CD8+ T-Cell Responses in Acute HIV-1 Infection: At the Crossroads of Viral and Host Genetics. Trends Immunol., 26(3):166-171, Mar 2005. PubMed ID: 15745859. Show all entries for this paper.


Displaying record number 1

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Walkerpercom1996 C. Wilson, B. Wilkes, D. Ruhl, and B. Walker. Personal communication, 1996. Defined in the context of the Pediatric AIDS Foundation ARIEL Project, a mother-infant HIV transmission study. Personal communication. Show all entries for this paper.


Displaying record number 55233

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-28 B1 and B2)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Subtype B, CRF01_AE
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B62, B8, Cw3
Country Netherlands
Experimental methods Other
Keywords subtype comparisons, computational epitope prediction, escape, superinfection, mutation acquisition

Notes

References

Kozaczynska2007 Karolina Kozaczynska, Marion Cornelissen, Peter Reiss, Fokla Zorgdrager, and Antoinette C. van der Kuyl. HIV-1 Sequence Evolution In Vivo after Superinfection with Three Viral Strains. Retrovirology, 4:59, 2007. PubMed ID: 17716368. Show all entries for this paper.


Displaying record number 55770

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 SF2, HXBc2/Bal R5)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Epitope Name KK9
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A3, B15, B7, Cw3, Cw6; A29, A3, B44, B7, Cw3, Cw7; A24, A3, B7, B8, Cw7
Country United States
Experimental methods Cytokine production, Degranulation, CD107a and b cell surface mobilization, Flow cytometric T-cell cytokine assay
Keywords supervised treatment interruptions (STI), variant cross-reactivity, characterizing CD8+ T cells, drug resistance

Notes

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


Displaying record number 56422

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9(p17)
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 58838

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Walkerpercom1996 C. Wilson, B. Wilkes, D. Ruhl, and B. Walker. Personal communication, 1996. Defined in the context of the Pediatric AIDS Foundation ARIEL Project, a mother-infant HIV transmission study. Personal communication. Show all entries for this paper.


Displaying record number 58839

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Walkerpercom1996 C. Wilson, B. Wilkes, D. Ruhl, and B. Walker. Personal communication, 1996. Defined in the context of the Pediatric AIDS Foundation ARIEL Project, a mother-infant HIV transmission study. Personal communication. Show all entries for this paper.


Displaying record number 54248

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name A3-KK9(p17)
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 2

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen in vitro stimulation or selection
Experimental methods  
Keywords dendritic cells

Notes

References

Zarling1999 A. L. Zarling, J. G. Johnson, R. W. Hoffman, and D. R. Lee. Induction of Primary Human CD8+ T Lymphocyte Responses In Vitro Using Dendritic Cells. J. Immunol., 162:5197-5204, 1999. PubMed ID: 10227993. Show all entries for this paper.


Displaying record number 3

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Brodie1999 S. J. Brodie, D. A. Lewinsohn, B. K. Patterson, D. Jiyamapa, J. Krieger, L. Corey, P. D. Greenberg, and S. R. Riddell. In Vivo Migration and Function of Transferred HIV-1-Specific Cytotoxic T cells [see comments]. Nat. Med., 5:34-41, 1999. PubMed ID: 9883837. Show all entries for this paper.


Displaying record number 4

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location (18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Brodie2000 S. J. Brodie, B. K. Patterson, D. A. Lewinsohn, K. Diem, D. Spach, P. D. Greenberg, S. R. Riddell, and L. Corey. HIV-Specific Cytotoxic T Lymphocytes Traffic to Lymph Nodes and Localize at Sites of HIV Replication and Cell Death. J. Clin. Invest., 105:1407-1417, 2000. PubMed ID: 10811848. Show all entries for this paper.


Displaying record number 5

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Wilson1999a C. C. Wilson, R. C. Brown, B. T. Korber, B. M. Wilkes, D. J. Ruhl, D. Sakamoto, K. Kunstman, K. Luzuriaga, I. C. Hanson, S. M. Widmayer, A. Wiznia, S. Clapp, A. J. Ammann, R. A. Koup, S. M. Wolinsky, and B. D. Walker. Frequent Detection of Escape from Cytotoxic T-Lymphocyte Recognition in Perinatal Human Immunodeficiency Virus (HIV) Type 1 Transmission: The Ariel Project for the Prevention of Transmission of HIV from Mother to Infant. J. Virol., 73:3975-3985, 1999. PubMed ID: 10196293. Show all entries for this paper.


Displaying record number 6

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 IIIB)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA 003: A*02, A*03, B*07, B*51
Experimental methods  
Keywords review, escape

Notes

References

Goulder1997 P. J. Goulder, A. K. Sewell, D. G. Lalloo, D. A. Price, J. A. Whelan, J. Evans, G. P. Taylor, G. Luzzi, P. Giangrande, R. E. Phillips, and A. J. McMichael. Patterns of Immunodominance in HIV-1-Specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-Identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation. J. Exp. Med., 8:1423-1433, 1997. Primary human immunodeficiency virus (HIV) infection is controlled principally by HIV-specific cytotoxic T lymphocytes (CTL) to a steady- state level of virus load, which strongly influences the ultimate rate of progression to disease. Epitope selection by CTL may be an important determinant of the degree of immune control over the virus. This report describes the CTL responses of two HLA-identical hemophiliac brothers who were exposed to identical batches of Factor VIII and became seropositive within 10 wk of one another. Both have HLA-A*0201. The CTL responses of the two siblings were very dissimilar, one donor making strong responses to two epitopes within p17 Gag (HLA-A*0201-restricted SLYNTVATL and HLA-A3-restricted RLRPGGKKK). The sibling responded to neither epitope, but made strong responses to two epitopes presented by HLA-B7. This was not the result of differences in presentation of the epitopes. However, mutations in both immunodominant epitopes of the p17 Gag responder were seen in proviral sequences of the nonresponder. We then documented the CTL responses to two HLA-A*0201-restricted epitopes, in Gag (SLYNTVATL) and Pol (ILKEPVHGV) in 22 other HIV-infected donors with HLA-A*0201. The majority (71\%) generated responses to the Gag epitope. In the 29\% of donors failing to respond to the Gag epitope in standard assays, there was evidence of low frequency memory CTL responses using peptide stimulation of PBMC, and most of these donors also showed mutations in or around the Gag epitope. PubMed ID: 9126923. Show all entries for this paper.

Goulder1997e P. Goulder, D. Price, M. Nowak, S. Rowland-Jones, R. Phillips, and A. McMichael. Co-Evolution of Human Immunodeficiency Virus and Cytotoxic T-Lymphocyte Responses. Immunol. Rev., 159:17-29, 1997. PubMed ID: 9416500. Show all entries for this paper.


Displaying record number 1110

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17( subtype B)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords  

Notes

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.


Displaying record number 1160

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17( SF2)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons, immunodominance

Notes

References

Goulder2000 P. J. Goulder, C. Brander, K. Annamalai, N. Mngqundaniso, U. Govender, Y. Tang, S. He, K. E. Hartman, C. A. O'Callaghan, G. S. Ogg, M. A. Altfeld, E. S. Rosenberg, H. Cao, S. A. Kalams, M. Hammond, M. Bunce, S. I. Pelton, S. A. Burchett, K. McIntosh, H. M. Coovadia, and B. D. Walker. Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children. J. Virol., 74:5679-90, 2000. PubMed ID: 10823876. Show all entries for this paper.


Displaying record number 1486

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART

Notes

References

Seth2001 A. Seth, J. Markee, A. Hoering, A. Sevin, D. E. Sabath, J. E. Schmitz, M. J. Kuroda, M. A. Lifton, M. S. Hirsch, A. C. Collier, N. L. Letvin, and M. J. McElrath. Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy. J. Infect. Dis., 183(5):722-9, 1 Mar 2001. PubMed ID: 11181148. Show all entries for this paper.


Displaying record number 1519

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26 SF2)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 1652

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 1759

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17( JRCSF)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Severino2000 M. E. Severino, N. V. Sipsas, P. T. Nguyen, S. A. Kalams, B. D. Walker, R. P. Johnson, and O. O. Yang. Inhibition of human immunodeficiency virus type 1 replication in primary CD4(+) T lymphocytes, monocytes, and dendritic cells by cytotoxic T lymphocytes. J. Virol., 74(14):6695-9, Jul 2000. URL: http://jvi.asm.org/cgi/content/full/74/14/6695. PubMed ID: 10864688. Show all entries for this paper.


Displaying record number 1837

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords dendritic cells

Notes

References

Ostrowski2000 M. A. Ostrowski, S. J. Justement, L. Ehler, S. B. Mizell, S. Lui, J. Mican, B. D. Walker, E. K. Thomas, R. Seder, and A. S. Fauci. The role of CD4+ T cell help and CD40 ligand in the in vitro expansion of HIV-1-specific memory cytotoxic CD8+ T cell responses. J. Immunol., 165(11):6133-41, 1 Dec 2000. URL: http://www.jimmunol.org/cgi/content/full/165/11/6133. PubMed ID: 11086046. Show all entries for this paper.


Displaying record number 52140

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name A3-KK9
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B7, Cw7
Experimental methods  
Keywords dynamics, supervised treatment interruptions (STI), immunodominance, acute/early infection

Notes

References

Yu2002b Xu G. Yu, Marylyn M. Addo, Eric S. Rosenberg, William R. Rodriguez, Paul K. Lee, Cecily A. Fitzpatrick, Mary N. Johnston, Daryld. Strick, Philip J. R. Goulder, Bruce D. Walker, and Marcus Altfeld. Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses Following Acute HIV-1 Infection. J. Virol., 76(17):8690-8701, Sep 2002. PubMed ID: 12163589. Show all entries for this paper.


Displaying record number 52970

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, Cw03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 59918

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(A*30)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59920

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(A*69)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59917

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52827

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Show epitope variants
Epitope Name A3-KK9 Gag
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords epitope processing, supervised treatment interruptions (STI), escape, early treatment, superinfection

Notes

References

Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.


Displaying record number 59919

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Epitope Name KK9
Species (MHC/HLA) human(B*82)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54672

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location p17(18-26)
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A*0101, A*0301, B*0801; A*0201, A*3101, B*3501, B*3905
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords HAART, ART, escape, viral fitness and reversion

Notes

References

Asquith2006 Becca Asquith, Charles T. T. Edwards, Marc Lipsitch, and Angela R. McLean. Inefficient Cytotoxic T Lymphocyte-Mediated Killing of HIV-1-Infected Cells In Vivo. PLoS Biol., 4(4):e90, Apr 2006. PubMed ID: 16515366. Show all entries for this paper.


Displaying record number 56205

HXB2 Location Gag(18-26)
p17(18-26)
DNA(841..867)
Gag Epitope Map
Author Location Gag
Epitope KIRLRPGGK Epitope Alignment
KIRLRPGGK epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Garrison2007 Keith E. Garrison, R. Brad Jones, Duncan A. Meiklejohn, Naveed Anwar, Lishomwa C. Ndhlovu, Joan M. Chapman, Ann L. Erickson, Ashish Agrawal, Gerald Spotts, Frederick M. Hecht, Seth Rakoff-Nahoum, Jack Lenz, Mario A. Ostrowski, and Douglas F. Nixon. T Cell Responses to Human Endogenous Retroviruses in HIV-1 Infection. PLoS Pathog., 3(11):e165, Nov 2007. PubMed ID: 17997601. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health