HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 56537

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HXB2 Location Pol(934-943)
Integrase(219-228)
DNA(4884..4913)
Pol Epitope Map
Author Location Pol
Epitope KIQNFRVYYR Epitope Alignment
KIQNFRVYYR epitope logo
Epitope Name Pol971
Subtype B
Species (MHC/HLA) human(A3)
Immunogen vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine antigen design

Vaccine Details

Vaccine type DNA, polyepitope
Vaccine component other

Notes

References

Wilson2008 Cara C. Wilson, Mark J. Newman, Brian D. Livingston, Samantha MaWhinney, Jeri E. Forster, Jim Scott, Robert T. Schooley, and Constance A. Benson. Clinical Phase 1 Testing of the Safety and Immunogenicity of an Epitope-Based DNA Vaccine in Human Immunodeficiency Virus Type 1-Infected Subjects Receiving Highly Active Antiretroviral Therapy. Clin. Vaccine Immunol., 15(6):986-994, Jun 2008. PubMed ID: 18400976. Show all entries for this paper.


Displaying record number 52721

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HXB2 Location Pol(934-943)
Integrase(219-228)
DNA(4884..4913)
Pol Epitope Map
Author Location Pol(934-943 SF2)
Epitope KIQNFRVYYR Epitope Alignment
KIQNFRVYYR epitope logo
Subtype B
Species (MHC/HLA) human(A*33:03)
Immunogen HIV-1 infection
Experimental methods Chromium-release assay
Keywords binding affinity, computational epitope prediction

Notes

References

Hossain2003 M Sohrab Hossain, Hiroko Tomiyama, Takafumi Inagawa, Setsuko Ida, Shinichi Oka, and Masafumi Takiguchi. Identification and Characterization of HLA-A*3303-Restricted, HIV Type 1 Pol- and Gag-Derived Cytotoxic T Cell Epitopes. AIDS Res. Hum. Retroviruses, 19(6):503-510, Jun 2003. PubMed ID: 12882660. Show all entries for this paper.


Displaying record number 1607

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HXB2 Location Pol(934-943)
Integrase(219-228)
DNA(4884..4913)
Pol Epitope Map
Author Location Pol(919-928)
Epitope KIQNFRVYYR Epitope Alignment
KIQNFRVYYR epitope logo
Species (MHC/HLA) human(A3 supertype)
Immunogen HIV-1 infection
Experimental methods  
Keywords supertype, rate of progression

Notes

References

Propato2001 A. Propato, E. Schiaffella, E. Vicenzi, V. Francavilla, L. Baloni, M. Paroli, L. Finocchi, N. Tanigaki, S. Ghezzi, R. Ferrara, R. Chesnut, B. Livingston, A. Sette, R. Paganelli, F. Aiuti, G. Poli, and V. Barnaba. Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity. Hum. Immunol., 62(6):561-76, Jun 2001. PubMed ID: 11390031. Show all entries for this paper.


Displaying record number 56514

Download this epitope record as JSON.

HXB2 Location Pol(934-943)
Integrase(219-228)
DNA(4884..4913)
Pol Epitope Map
Author Location Pol
Epitope KIQNFRVYYR Epitope Alignment
KIQNFRVYYR epitope logo
Epitope Name Pol971
Subtype A, B, C, D
Species (MHC/HLA) human, mouse(A3 supertype)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords binding affinity, supertype, vaccine-induced immune responses, HLA cross-presentation

Notes

References

Wilson2003 Cara C. Wilson, Denise McKinney, Michelle Anders, Samantha MaWhinney, Jeri Forster, Claire Crimi, Scott Southwood, Alessandro Sette, Robert Chesnut, Mark J Newman, and Brian D Livingston. Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1. J. Immunol., 171(10):5611-5623, 15 Nov 2003. PubMed ID: 14607970. Show all entries for this paper.


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