Search CTL/CD8+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 482

Download this epitope record as JSON.

HXB2 Location	Pol(356-364) RT(201-209) DNA(3150..3176)	Pol Epitope Map
Author Location	RT(201-209)
Epitope	KIEELRQHL	Epitope Alignment
Species (MHC/HLA)	human(A2)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

• Of 98 patients in cross-sectional analysis, 78% had CTL against pol -- RT was more immunogenic than Integrase and Protease (81%, 51%, and 24% of 37 patients, respectively)
• New clusters of epitopes were defined utilizing different HLA molecules.

References

Haas1998 G. Haas, A. Samri, E. Gomard, A. Hosmalin, J. Duntze, J. M. Bouley, H. G. Ihlenfeldt, C. Katlama, and B. Autran. Cytotoxic T Cell Responses to HIV-1 Reverse Transcriptase, Integrase and Protease. AIDS, 12(12):1427-1436, 1998. PubMed ID: 9727563. Show all entries for this paper.