HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 56300

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HXB2 Location Gag(335-343)
p24(203-211)
DNA(1792..1818)
Gag Epitope Map
Author Location p24(335-343 SF2, HXBc2/Bal R5)
Epitope KALGPAATL Epitope Alignment
KALGPAATL epitope logo
Subtype B
Species (MHC/HLA) human(B15, Cw3)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A3, B15, B7, Cw3, Cw6
Country United States
Experimental methods Cytokine production, Degranulation, CD107a and b cell surface mobilization, Flow cytometric T-cell cytokine assay
Keywords supervised treatment interruptions (STI), immunodominance, characterizing CD8+ T cells, drug resistance

Notes

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


Displaying record number 61787

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HXB2 Location Gag(335-343)
p24(203-211)
DNA(1792..1818)
Gag Epitope Map
Author Location  
Epitope KALGPAATL Epitope Alignment
KALGPAATL epitope logo
Epitope Name KL9
Subtype B
Species (MHC/HLA) human(C*03)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 61788

Download this epitope record as JSON.

HXB2 Location Gag(335-343)
p24(203-211)
DNA(1792..1818)
Gag Epitope Map
Author Location  
Epitope KALGPAATL Epitope Alignment
KALGPAATL epitope logo
Epitope Name KL9
Subtype B
Species (MHC/HLA) human(C*08)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 53248

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HXB2 Location Gag(335-343)
p24(203-211)
DNA(1792..1818)
Gag Epitope Map
Author Location Gag(335-343 SUMA)
Epitope KALGPAATL Epitope Alignment
KALGPAATL epitope logo
Epitope Name Gag KL9
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA SUMA: A*11:03, A*24:02, B*14:02, B*15:01, C*08:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords dynamics, acute/early infection, autologous responses, optimal epitope

Notes

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.

Yang2019 Yiding Yang, and Vitaly V. Ganusov. Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection. Microorganisms, 7(3):microorganisms7030069 doi, Mar 2019. PubMed ID: 30836625 Show all entries for this paper.


Displaying record number 58208

Download this epitope record as JSON.

HXB2 Location Gag(335-343)
p24(203-211)
DNA(1792..1818)
Gag Epitope Map
Author Location Gag/Pol(334- CDC-451)
Epitope KALGPAATL Epitope Alignment
KALGPAATL epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen computer prediction
Experimental methods  
Keywords T-cell crossreactivity to human proteins

Notes

References

Lucchese2011 Guglielmo Lucchese, Angela Stufano, Michele Calabro, and Darja Kanduc. Charting the Peptide Crossreactome between HIV-1 and the Human Proteome. Front. Biosci. (Elite Ed.), 3E:1385-1400, 2011. PubMed ID: 21622144. Show all entries for this paper.


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