HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 52939

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HXB2 Location Nef(82-91)
DNA(9040..9069)
Nef Epitope Map
Author Location Nef(82-91)
Epitope KAALDLSHFL Epitope Alignment
KAALDLSHFL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A2)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Proliferation
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade LAI
Vaccine component Env, Gag, Nef
Adjuvant QS21

Notes

References

Gahery-Segard2003 Hanne Gahéry-Ségard, Gilles Pialoux, Suzanne Figueiredo, Céline Igéa, Mathieu Surenaud, Jessintha Gaston, Helene Gras-Masse, Jean-Paul Lévy, and Jean-Gérard Guillet. Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized. J. Virol., 77(20):11220-11231, Oct 2003. PubMed ID: 14512570. Show all entries for this paper.


Displaying record number 59211

Download this epitope record as JSON.

HXB2 Location Nef(82-91)
DNA(9040..9069)
Nef Epitope Map
Author Location Nef(82-91)
Epitope KAALDLSHFL Epitope Alignment
KAALDLSHFL epitope logo
Show epitope variants
Epitope Name KL10
Subtype B
Species (MHC/HLA) human(B*57:01)
Immunogen HIV-1 infection
Patient MHC/HLA P2: B*57:01; P3: B*57:01; P4: B*57:01; P6: B*57:01
Country United States
Experimental methods Other
Keywords dynamics, rate of progression, elite controllers

Notes

References

Buggert2014 Marcus Buggert, Melissa M. Norström, Marco Salemi, Frederick M. Hecht, and Annika C. Karlsson. Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. J. Immunol., 192(10):4685-4696, 15 May 2014. PubMed ID: 24740510. Show all entries for this paper.


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