HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 56878

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HXB2 Location Nef(82-90)
DNA(9040..9066)
Nef Epitope Map
Author Location  
Epitope KAALDLSHF Epitope Alignment
KAALDLSHF epitope logo
Subtype B
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, elite controllers

Notes

References

Bailey2009 Justin R. Bailey, Timothy P. Brennan, Karen A. O'Connell, Robert F. Siliciano, and Joel N. Blankson. Evidence of CD8+ T-Cell-Mediated Selective Pressure on Human Immunodeficiency Virus Type 1 nef in HLA-B*57+ elite suppressors. J. Virol., 83(1):88-97, Jan 2009. PubMed ID: 18945771. Show all entries for this paper.


Displaying record number 56632

Download this epitope record as JSON.

HXB2 Location Nef(82-90)
DNA(9040..9066)
Nef Epitope Map
Author Location Nef(82-90)
Epitope KAALDLSHF Epitope Alignment
KAALDLSHF epitope logo
Show epitope variants
Species (MHC/HLA) human(B*57:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords escape, acute/early infection

Notes

References

Goonetilleke2009 Nilu Goonetilleke, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, Gerald H. Learn, Emma L. Turnbull, Maria G Salazar, Kent J Weinhold, Stephen Moore, CHAVI Clinical Core B, Norman Letvin, Barton F. Haynes, Myron S. Cohen, Peter Hraber, Tanmoy Bhattacharya, Persephone Borrow, Alan S. Perelson, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, and Andrew J. McMichael. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med., 206(6):1253-1272, 8 Jun 2009. PubMed ID: 19487423. Show all entries for this paper.


Displaying record number 61069

Download this epitope record as JSON.

HXB2 Location Nef(82-90)
DNA(9040..9066)
Nef Epitope Map
Author Location Nef(82-90)
Epitope KAALDLSHF Epitope Alignment
KAALDLSHF epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA CH077: A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords computational epitope prediction, escape, acute/early infection, mutation acquisition

Notes

References

Barton2016 John P. Barton, Nilu Goonetilleke, Thomas C. Butler, Bruce D. Walker, Andrew J. McMichael, and Arup K. Chakraborty. Relative Rate and Location of Intra-Host HIV Evolution to Evade Cellular Immunity Are Predictable. Nat. Commun., 7:11660, 23 May 2016. PubMed ID: 27212475. Show all entries for this paper.


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