HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 58680

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HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location  
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supertype, HLA cross-presentation, optimal epitope

Notes

References

Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.


Displaying record number 53280

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HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location ( C consensus)
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 54011

Download this epitope record as JSON.

HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location ( C consensus)
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 56246

Download this epitope record as JSON.

HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location  
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01, A*24:02)
Immunogen HIV-1 infection
Patient MHC/HLA A*23:01, B*08:01, B*15:10, C*07:01, C*16:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords rate of progression

Notes

References

Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.


Displaying record number 54012

Download this epitope record as JSON.

HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location ( C consensus)
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Subtype C
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 61855

Download this epitope record as JSON.

HXB2 Location Pol(496-504)
RT(341-349)
DNA(3570..3596)
Pol Epitope Map
Author Location  
Epitope IYQEPFKNL Epitope Alignment
IYQEPFKNL epitope logo
Show epitope variants
Epitope Name IL9
Subtype B
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA KI-1105: A*24:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses

Notes

References

Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.


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