HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 1553

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location RT(375-383 SF2)
Epitope ITTESIVIW Epitope Alignment
ITTESIVIW epitope logo
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 60961

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location RT(375-383)
Epitope ITTESIVIW Epitope Alignment
ITTESIVIW epitope logo
Subtype B
Species (MHC/HLA) human(B*57:01)
Immunogen HIV-1 infection
Patient MHC/HLA 67200: A*01:01, A*24:02, B*08:01, B*57:01, C*06:02, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 550

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location RT(375-383 LAI)
Epitope ITTESIVIW Epitope Alignment
ITTESIVIW epitope logo
Subtype B
Species (MHC/HLA) human(B*57:01, B*58:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression

Notes

References

Klein1998 M. R. Klein, S. H. van der Burg, E. Hovenkamp, A. M. Holwerda, J. W. Drijfhout, C. J. Melief, and F. Miedema. Characterization of HLA-B57-Restricted Human Immunodeficiency Virus Type 1 Gag- and RT-Specific Cytotoxic T Lymphocyte Responses. J. Gen. Virol., 79(Pt 9):2191-2201, 1998. PubMed ID: 9747728. Show all entries for this paper.

vanderBurg1997 S. H. van der Burg, M. R. Klein, O. Pontesilli, A. M. Holwerda, J. Drijfhout, W. M. Kast, F. Miedema, and C. J. M. Melief. HIV-1 Reverse Transcriptase-Specific CTL against Conserved Epitopes Do Not Protect against Progression to AIDS. J. Immunol., 159:3648-3654, 1997. PubMed ID: 9317165. Show all entries for this paper.


Displaying record number 61188

Download this epitope record as JSON.

HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location Pol(530-538)
Epitope ITTESIVIW Epitope Alignment
ITTESIVIW epitope logo
Show epitope variants
Epitope Name IW9
Subtype B
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 58063

Download this epitope record as JSON.

HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location Pol
Epitope ITTESIVIW Epitope Alignment
ITTESIVIW epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


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