HIV molecular immunology database
Found 20 matching records:
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(A*01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(A*11) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(A*25) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(A*31) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | ||
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Subtype | B | |
Species (MHC/HLA) | human(A*68) | |
Immunogen | HIV-1 infection | |
Country | Barbados, Haiti, Jamaica | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | mother-to-infant transmission, elite controllers |
Schneidewind2009 Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, and Margaret E. Feeney. Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant. J. Virol., 83(17):8616-8627, Sep 2009. PubMed ID: 19515764. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | A68-IR11(Tat) | |
Species (MHC/HLA) | human(A68) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-48) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A68) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | early-expressed proteins |
Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*68:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Degranulation, CD107a and b cell surface mobilization, Other | |
Keywords | binding affinity, epitope processing, kinetics, characterizing CD8+ T cells |
Gostick2007 Emma Gostick, David K. Cole, Sarah L. Hutchinson, Linda Wooldridge, Sabrina Tafuro, Bruno Laugel, Anna Lissina, Annette Oxenius, Jonathan M. Boulter, David A. Price, and Andrew K. Sewell. Functional and Biophysical Characterization of an HLA-A*6801-Restricted HIV-Specific T Cell Receptor. Eur. J. Immunol., 37(2):479-486, Feb 2007. PubMed ID: 17273992. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-48) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | Tat-4.8 | |
Species (MHC/HLA) | human(A*68:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | assay or method development |
Oxenius2002a Annette Oxenius, Bent K. Jakobsen, Philippa J. Easterbrook, Jonathan M. Boulter, Tin Tun, Anele Waters, Juliet Agudelo, Martin Barnardo, Rodney E. Phillips, and David A. Price. Complete Mapping of a Novel HLA A*6801-Restricted HIV-1 Tat Epitope Directly with a Rapid Modified Enzyme-Linked Immunospot Assay. AIDS, 16(9):1285-1287, 14 Jun 2002. PubMed ID: 12045495. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-48) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | ITK | |
Species (MHC/HLA) | human(A*68:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A2, A68.1, B*07, B*35:03, C*04:01, C*07:02, DQ2, DQ6, DR15, DR17, DR51, DR52 | |
Experimental methods | CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, escape |
Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*68:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*68:01) | |
Immunogen | peptide-HLA interaction | |
Experimental methods | Cytokine production, Flow cytometric T-cell cytokine assay | |
Keywords | binding affinity, co-receptor, characterizing CD8+ T cells |
Laugel2007a Bruno Laugel, David A. Price, Anita Milicic, and Andrew K. Sewell. CD8 Exerts Differential Effects on the Deployment of Cytotoxic T Lymphocyte Effector Functions. Eur. J. Immunol., 37(4):905-913, Apr 2007. PubMed ID: 17393387. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*15:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*35:02, B*35:03, B*53:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*49) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(B*81) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(39-49) DNA(5945..5977) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(39-49) | |
Epitope |
ITKGLGISYGR
|
Epitope Alignment
|
Epitope Name | IR11 | |
Species (MHC/HLA) | human(C*14) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.