HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 20 matching records:

Displaying record number 59855

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(A*01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59853

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59857

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(A*25)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59848

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(A*31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54278

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name A68-IR11(Tat)
Species (MHC/HLA) human(A68)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 52415

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(38-48)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Subtype B
Species (MHC/HLA) human(A68)
Immunogen HIV-1 infection
Experimental methods  
Keywords early-expressed proteins

Notes

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.


Displaying record number 57284

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location  
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Subtype B
Species (MHC/HLA) human(A*68)
Immunogen HIV-1 infection
Country Barbados, Haiti, Jamaica
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords mother-to-infant transmission, elite controllers

Notes

References

Schneidewind2009 Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, and Margaret E. Feeney. Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant. J. Virol., 83(17):8616-8627, Sep 2009. PubMed ID: 19515764. Show all entries for this paper.


Displaying record number 54864

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Subtype B
Species (MHC/HLA) human(A*6801)
Immunogen peptide-HLA interaction
Experimental methods Cytokine production, Flow cytometric T-cell cytokine assay
Keywords binding affinity, co-receptor, characterizing CD8+ T cells

Notes

References

Laugel2007a Bruno Laugel, David A. Price, Anita Milicic, and Andrew K. Sewell. CD8 Exerts Differential Effects on the Deployment of Cytotoxic T Lymphocyte Effector Functions. Eur. J. Immunol., 37(4):905-913, Apr 2007. PubMed ID: 17393387. Show all entries for this paper.


Displaying record number 52173

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(38-48)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name Tat-4.8
Species (MHC/HLA) human(A*6801)
Immunogen HIV-1 infection
Experimental methods  
Keywords assay or method development

Notes

References

Oxenius2002a Annette Oxenius, Bent K. Jakobsen, Philippa J. Easterbrook, Jonathan M. Boulter, Tin Tun, Anele Waters, Juliet Agudelo, Martin Barnardo, Rodney E. Phillips, and David A. Price. Complete Mapping of a Novel HLA A*6801-Restricted HIV-1 Tat Epitope Directly with a Rapid Modified Enzyme-Linked Immunospot Assay. AIDS, 16(9):1285-1287, 14 Jun 2002. PubMed ID: 12045495. Show all entries for this paper.


Displaying record number 53418

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(38-48)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Show epitope variants
Epitope Name ITK
Species (MHC/HLA) human(A*6801)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A68.1, B*07, B*3503, Cw*0401, Cw*0702, DQ2, DQ6, DR15, DR17, DR51, DR52
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ
Keywords rate of progression, escape

Notes

References

Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.


Displaying record number 52546

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Species (MHC/HLA) human(A*6801)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 54589

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(38-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Species (MHC/HLA) human(A*6801)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Degranulation, CD107a and b cell surface mobilization, Other
Keywords binding affinity, epitope processing, kinetics, characterizing CD8+ T cells

Notes

References

Gostick2007 Emma Gostick, David K. Cole, Sarah L. Hutchinson, Linda Wooldridge, Sabrina Tafuro, Bruno Laugel, Anna Lissina, Annette Oxenius, Jonathan M. Boulter, David A. Price, and Andrew K. Sewell. Functional and Biophysical Characterization of an HLA-A*6801-Restricted HIV-Specific T Cell Receptor. Eur. J. Immunol., 37(2):479-486, Feb 2007. PubMed ID: 17273992. Show all entries for this paper.


Displaying record number 59851

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59849

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59847

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59854

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59856

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*49)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59852

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(B*81)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59850

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59846

HXB2 Location Tat(39-49)
DNA(5945..5977)
Tat Epitope Map
Author Location Tat(39-49)
Epitope ITKGLGISYGR Epitope Alignment
ITKGLGISYGR epitope logo
Epitope Name IR11
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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