HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 17 matching records:

Displaying record number 59841

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59840

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(B*3501, B*3508)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59839

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54391

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name B57-IF9(Vif)
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 55607

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Subtype B
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords computational epitope prediction

Notes

References

Schellens2008 Ingrid M. M. Schellens, Can Kesmir, Frank Miedema, Debbie van Baarle, and José A. M. Borghans. An Unanticipated Lack of Consensus Cytotoxic T Lymphocyte Epitopes in HIV-1 Databases: The Contribution of Prediction Programs. AIDS, 22(1):33-37, 2 Jan 2008. PubMed ID: 18090389. Show all entries for this paper.


Displaying record number 53650

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location  
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Species (MHC/HLA) human(B*5801, B57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Feeney2005a Margaret E. Feeney, Yanhua Tang, Katja Pfafferott, Kathleen A. Roosevelt, Rika Draenert, Alicja Trocha, Xu G. Yu, Cori Verrill, Todd Allen, Corey Moore, Simon Mallal, Sandra Burchett, Kenneth McIntosh, Stephen I. Pelton, M. Anne St. John, Rohan Hazra, Paul Klenerman, Marcus Altfeld, Bruce D. Walker, and Philip J. R. Goulder. HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response. J. Immunol., 174(12):7524-7530, 15 Jun 2005. PubMed ID: 15944251. Show all entries for this paper.


Displaying record number 62126

HXB2 Location Vif(31-39) Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name B*57-IF9
Species (MHC/HLA) human(B*57)
Immunogen computer prediction
Country Argentina
Experimental methods Other, Relative replication capacity assay
Keywords binding affinity, structure, assay or method development, contact residues

Notes

References

Gaiha2019 Gaurav D. Gaiha, Elizabeth J. Rossin, Jonathan Urbach, Christian Landeros, David R. Collins, Chioma Nwonu, Itai Muzhingi, Melis N. Anahtar, Olivia M. Waring, Alicja Piechocka-Trocha, Michael Waring, Daniel P. Worrall, Musie S. Ghebremichael, Ruchi M. Newman, Karen A. Power, Todd M. Allen, James Chodosh, and Bruce D. Walker. Structural Topology Defines Protective CD8+ T Cell Epitopes in the HIV Proteome. Science, 364(6439):480-484, 3 May 2019. PubMed ID: 31048489. Show all entries for this paper.


Displaying record number 54385

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location  
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape

Notes

References

Bailey2006 Justin R. Bailey, Thomas M. Williams, Robert F. Siliciano, and Joel N. Blankson. Maintenance of Viral Suppression in HIV-1-Infected HLA-B*57+ Elite Suppressors Despite CTL Escape Mutations. J. Exp. Med., 203(5):1357-1369, 15 May 2006. PubMed ID: 16682496. Show all entries for this paper.


Displaying record number 54825

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vpr(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name vifIF9
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Country Kenya, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords TCR usage, structure, characterizing CD8+ T cells

Notes

References

Gillespie2006 Geraldine M. A. Gillespie, Guillaume Stewart-Jones, Jaya Rengasamy, Tara Beattie, Job J. Bwayo, Francis A. Plummer, Rupert Kaul, Andrew J. McMichael, Philippa Easterbrook, Tao Dong, E. Yvonne Jones, and Sarah L. Rowland-Jones. Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection. J. Immunol., 177(6):3893-3902, 15 Sep 2006. PubMed ID: 16951352. Show all entries for this paper.


Displaying record number 61568

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name B57-IF9(vif)
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Patient MHC/HLA AC-43: A*24, A*31, B*14, B*57, Cw*07, Cw*08
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords acute/early infection, protective allele

Notes

References

Altfeld2003a Marcus Altfeld, Marylyn M. Addo, Eric S. Rosenberg, Frederick M. Hecht, Paul K. Lee, Martin Vogel, Xu G. Yu, Rika Draenert, Mary N. Johnston, Daryld Strick, Todd M. Allen, Margaret E. Feeney, James O. Kahn, Rafick P. Sekaly, Jay A. Levy, Jürgen K. Rockstroh, Philip J. Goulder, and Bruce D. Walker. Influence of HLA-B57 on Clinical Presentation and Viral Control during Acute HIV-1 Infection. AIDS, 17(18):2581-2591, 5 Dec 2003. PubMed ID: 14685052. Show all entries for this paper.


Displaying record number 61689

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords review

Notes

References

Silver2017 Zachary A. Silver and David I. Watkins. The Role of MHC Class I Gene Products in SIV Infection of Macaques. Immunogenetics, 69(8-9):511-519, Aug 2017. PubMed ID: 28695289. Show all entries for this paper.


Displaying record number 52401

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Subtype B
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Experimental methods  
Keywords early-expressed proteins

Notes

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.


Displaying record number 58992

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Subtype B
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Country Argentina
Experimental methods Other
Keywords mutation acquisition

Notes

References

Bartha2013 István Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F. Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M. Allen, Viktor Müller, P. Richard Harrigan, David Heckerman, Amalio Telenti, and Jacques Fellay. A Genome-to-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control. eLife, 2:e01123, 2013. PubMed ID: 24171102. Show all entries for this paper.


Displaying record number 52599

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Species (MHC/HLA) human(B*5701)
Immunogen  
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 1268

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39 SF2)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Altfeld2001c M. Altfeld, M. M. Addo, R. L. Eldridge, X. G. Yu, S. Thomas, A. Khatri, D. Strick, M. N. Phillips, G. B. Cohen, S. A. Islam, S. A. Kalams, C. Brander, P. J. Goulder, E. S. Rosenberg, B. D. Walker, and The HIV Study Collaboration.. Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol., 167(5):2743-52, 1 Sep 2001. URL: http://www.jimmunol.org/cgi/content/full/167/5/2743. PubMed ID: 11509618. Show all entries for this paper.


Displaying record number 59842

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location Vif(31-39)
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Epitope Name IF9
Species (MHC/HLA) human(C*06)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52058

HXB2 Location Vif(31-39)
DNA(5131..5157)
Vif Epitope Map
Author Location  
Epitope ISKKAKGWF Epitope Alignment
ISKKAKGWF epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords epitope processing, escape

Notes

References

Yusim2002 Karina Yusim, Can Kesmir, Brian Gaschen, Marylyn M. Addo, Marcus Altfeld, S\oren Brunak, Alexandre Chigaev, Vincent Detours, and Bette T. Korber. Clustering Patterns of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1 (HIV-1) Proteins Reveal Imprints of Immune Evasion on HIV-1 Global Variation. J. Virol., 76(17):8757-8768, Sep 2002. PubMed ID: 12163596. Show all entries for this paper.


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