HIV molecular immunology database
Found 17 matching records:
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(B*18) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(B*35:01, B*35:08) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(B*35:02, B*35:03, B*53:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | B57-IF9(vif) | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | AC-43: A*24, A*31, B*14, B*57, C*07, C*08 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | acute/early infection, protective allele |
Altfeld2003a Marcus Altfeld, Marylyn M. Addo, Eric S. Rosenberg, Frederick M. Hecht, Paul K. Lee, Martin Vogel, Xu G. Yu, Rika Draenert, Mary N. Johnston, Daryld Strick, Todd M. Allen, Margaret E. Feeney, James O. Kahn, Rafick P. Sekaly, Jay A. Levy, Jürgen K. Rockstroh, Philip J. Goulder, and Bruce D. Walker. Influence of HLA-B57 on Clinical Presentation and Viral Control during Acute HIV-1 Infection. AIDS, 17(18):2581-2591, 5 Dec 2003. PubMed ID: 14685052. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vpr(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | vifIF9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | Kenya, United Kingdom | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | TCR usage, structure, characterizing CD8+ T cells |
Gillespie2006 Geraldine M. A. Gillespie, Guillaume Stewart-Jones, Jaya Rengasamy, Tara Beattie, Job J. Bwayo, Francis A. Plummer, Rupert Kaul, Andrew J. McMichael, Philippa Easterbrook, Tao Dong, E. Yvonne Jones, and Sarah L. Rowland-Jones. Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection. J. Immunol., 177(6):3893-3902, 15 Sep 2006. PubMed ID: 16951352. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | ||
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape |
Bailey2006 Justin R. Bailey, Thomas M. Williams, Robert F. Siliciano, and Joel N. Blankson. Maintenance of Viral Suppression in HIV-1-Infected HLA-B*57+ Elite Suppressors Despite CTL Escape Mutations. J. Exp. Med., 203(5):1357-1369, 15 May 2006. PubMed ID: 16682496. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | B*57-IF9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | computer prediction | |
Country | Argentina | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | binding affinity, structure, assay or method development, contact residues |
Gaiha2019 Gaurav D. Gaiha, Elizabeth J. Rossin, Jonathan Urbach, Christian Landeros, David R. Collins, Chioma Nwonu, Itai Muzhingi, Melis N. Anahtar, Olivia M. Waring, Alicja Piechocka-Trocha, Michael Waring, Daniel P. Worrall, Musie S. Ghebremichael, Ruchi M. Newman, Karen A. Power, Todd M. Allen, James Chodosh, and Bruce D. Walker. Structural Topology Defines Protective CD8+ T Cell Epitopes in the HIV Proteome. Science, 364(6439):480-484, 3 May 2019. PubMed ID: 31048489. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Subtype | B | |
Species (MHC/HLA) | human(B57) | |
Immunogen | HIV-1 infection | |
Country | Netherlands | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | computational epitope prediction |
Schellens2008 Ingrid M. M. Schellens, Can Kesmir, Frank Miedema, Debbie van Baarle, and José A. M. Borghans. An Unanticipated Lack of Consensus Cytotoxic T Lymphocyte Epitopes in HIV-1 Databases: The Contribution of Prediction Programs. AIDS, 22(1):33-37, 2 Jan 2008. PubMed ID: 18090389. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | B57-IF9(Vif) | |
Species (MHC/HLA) | human(B57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | ||
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*58:01, B57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | responses in children, mother-to-infant transmission, escape |
Feeney2005a Margaret E. Feeney, Yanhua Tang, Katja Pfafferott, Kathleen A. Roosevelt, Rika Draenert, Alicja Trocha, Xu G. Yu, Cori Verrill, Todd Allen, Corey Moore, Simon Mallal, Sandra Burchett, Kenneth McIntosh, Stephen I. Pelton, M. Anne St. John, Rohan Hazra, Paul Klenerman, Marcus Altfeld, Bruce D. Walker, and Philip J. R. Goulder. HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response. J. Immunol., 174(12):7524-7530, 15 Jun 2005. PubMed ID: 15944251. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | review |
Silver2017 Zachary A. Silver and David I. Watkins. The Role of MHC Class I Gene Products in SIV Infection of Macaques. Immunogenetics, 69(8-9):511-519, Aug 2017. PubMed ID: 28695289. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39 SF2) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Altfeld2001c M. Altfeld, M. M. Addo, R. L. Eldridge, X. G. Yu, S. Thomas, A. Khatri, D. Strick, M. N. Phillips, G. B. Cohen, S. A. Islam, S. A. Kalams, C. Brander, P. J. Goulder, E. S. Rosenberg, B. D. Walker, and The HIV Study Collaboration.. Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol., 167(5):2743-52, 1 Sep 2001. URL: http://www.jimmunol.org/cgi/content/full/167/5/2743. PubMed ID: 11509618. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Country | Argentina | |
Experimental methods | Other | |
Keywords | mutation acquisition |
Bartha2013 István Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F. Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M. Allen, Viktor Müller, P. Richard Harrigan, David Heckerman, Amalio Telenti, and Jacques Fellay. A Genome-to-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control. eLife, 2:e01123, 2013. PubMed ID: 24171102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 00870: A*11:01, A*24:02, B*35:01, B*55:01, C*03:03, C*04:01 | |
Experimental methods | ||
Keywords | early-expressed proteins |
Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | Vif(31-39) | |
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Epitope Name | IF9 | |
Species (MHC/HLA) | human(C*06) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vif(31-39) DNA(5131..5157) |
Vif Epitope Map |
---|---|---|
Author Location | ||
Epitope |
ISKKAKGWF
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | epitope processing, escape |
Yusim2002 Karina Yusim, Can Kesmir, Brian Gaschen, Marylyn M. Addo, Marcus Altfeld, S\oren Brunak, Alexandre Chigaev, Vincent Detours, and Bette T. Korber. Clustering Patterns of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1 (HIV-1) Proteins Reveal Imprints of Immune Evasion on HIV-1 Global Variation. J. Virol., 76(17):8757-8768, Sep 2002. PubMed ID: 12163596. Show all entries for this paper.