HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 59805

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59810

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54350

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name B15-IY10(RT)
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 57387

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location Pol(464-473)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen in vitro stimulation or selection, HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development, chronic infection

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 62535

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location Pol(464-473)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Patient MHC/HLA S00009: A*03, A*26, B*15, B*38, C*03, C*12
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dynamics, chronic infection

Notes

References

Balamurugan2017 Arumugam Balamurugan, Deon Claiborne, Hwee L. Ng, and Otto O. Yang. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth. J. Virol., 91(16), 15 Aug 2017. PubMed ID: 28592539. Show all entries for this paper.


Displaying record number 59806

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(B*15:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59808

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(B*15:03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1817

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Species (MHC/HLA) human(B*62)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 59807

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(B*81)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59809

Download this epitope record as JSON.

HXB2 Location Pol(464-473)
RT(309-318)
DNA(3474..3503)
Pol Epitope Map
Author Location RT Pol(309-318)
Epitope IKLEPVHGVY Epitope Alignment
IKLEPVHGVY epitope logo
Epitope Name IY10
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health