HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 57312

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HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location p24(134-143)
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Epitope Name IR10
Subtype B
Species (MHC/HLA) human(A*03, A*11)
Immunogen peptide-HLA interaction
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other
Keywords epitope processing

Notes

References

Tenzer2009 Stefan Tenzer, Edmund Wee, Anne Burgevin, Guillaume Stewart-Jones, Lone Friis, Kasper Lamberth, Chih-hao Chang, Mikkel Harndahl, Mirjana Weimershaus, Jan Gerstoft, Nadja Akkad, Paul Klenerman, Lars Fugger, E. Yvonne Jones, Andrew J. McMichael, Søren Buus, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. Antigen Processing Influences HIV-Specific Cytotoxic T Lymphocyte Immunodominance. Nat. Immunol., 10(6):636-646, Jun 2009. PubMed ID: 19412183. Show all entries for this paper.


Displaying record number 60663

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HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location p24(134-142)
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Epitope Name IR-10
Subtype B, C
Species (MHC/HLA) human(A*03, A*11, A*33)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 52955

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HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location Gag(266-275)
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Subtype B
Species (MHC/HLA) human(A11, A3)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Proliferation
Keywords vaccine-induced immune responses, variant cross-reactivity

Vaccine Details

Vaccine type lipopeptide
Vaccine strain B clade LAI
Vaccine component Env, Gag, Nef
Adjuvant QS21

Notes

References

Gahery-Segard2003 Hanne Gahéry-Ségard, Gilles Pialoux, Suzanne Figueiredo, Céline Igéa, Mathieu Surenaud, Jessintha Gaston, Helene Gras-Masse, Jean-Paul Lévy, and Jean-Gérard Guillet. Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized. J. Virol., 77(20):11220-11231, Oct 2003. PubMed ID: 14512570. Show all entries for this paper.


Displaying record number 55879

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HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location Gag
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Subtype A, B, C
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons

Notes

References

Gudmundsdotter2008 L. Gudmundsdotter, D. Bernasconi, B. Hejdeman, E. Sandstrom, A. Alaeus, K. Lidman, B. Ensoli, B. Wahren, and S. Buttò. Cross-Clade Immune Responses to Gag p24 in Patients Infected with Different HIV-1 Subtypes and Correlation with HLA Class I and II Alleles. Vaccine, 26(40):5182-5187, 19 Sep 2008. PubMed ID: 18479789. Show all entries for this paper.


Displaying record number 298

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HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location p24( subtype B)
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Subtype B
Species (MHC/HLA) human(A33)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords subtype comparisons

Notes

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 55959

Download this epitope record as JSON.

HXB2 Location Gag(266-275)
p24(134-143)
DNA(1585..1614)
Gag Epitope Map
Author Location p24
Epitope IILGLNKIVR Epitope Alignment
IILGLNKIVR epitope logo
Epitope Name IR10(p24)
Subtype B
Species (MHC/HLA) human(A33)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords optimal epitope, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


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