HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 58608

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HXB2 Location Pol(918-926)
Integrase(203-211)
DNA(4836..4862)
Pol Epitope Map
Author Location Integrase(202-212)
Epitope IIATDIQTK Epitope Alignment
IIATDIQTK epitope logo
Epitope Name IK9
Subtype B
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Country China
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61874

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HXB2 Location Pol(918-926)
Integrase(203-211)
DNA(4836..4862)
Pol Epitope Map
Author Location  
Epitope IIATDIQTK Epitope Alignment
IIATDIQTK epitope logo
Epitope Name IK9
Subtype B
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses

Notes

References

Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.


Displaying record number 55244

Download this epitope record as JSON.

HXB2 Location Pol(918-926)
Integrase(203-211)
DNA(4836..4862)
Pol Epitope Map
Author Location Integrase(202-212)
Epitope IIATDIQTK Epitope Alignment
IIATDIQTK epitope logo
Epitope Name IK9
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 62854

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HXB2 Location Pol(918-926)
Integrase(203-211)
DNA(4836..4862)
Pol Epitope Map
Author Location Integrase(203-211)
Epitope IIATDIQTK Epitope Alignment
IIATDIQTK epitope logo
Epitope Name IK9
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection, engineered
Experimental methods Other, Relative replication capacity assay
Keywords acute/early infection, HLA associated polymorphism, chronic infection, protective allele

Notes

References

Ojwach2018 Doty B. A. Ojwach, Daniel MacMillan, Tarylee Reddy, Vladimir Novitsky, Zabrina L. Brumme, Mark A. Brockman, Thumbi Ndung'u, and Jaclyn K. Mann. Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. J. Virol., 92(19), 1 Oct 2018. PubMed ID: 29997209. Show all entries for this paper.


Displaying record number 62897

Download this epitope record as JSON.

HXB2 Location Pol(918-926)
Integrase(203-211)
Pol Epitope Map
Author Location Integrase(203-211)
Epitope IIATDIQTK Epitope Alignment
IIATDIQTK epitope logo
Show epitope variants
Epitope Name IK9
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection, engineered
Experimental methods Other, Relative replication capacity assay
Keywords vaccine antigen design

Notes

References

Ojwach2021 Doty B. A. Ojwach, Paradise Madlala, Michelle Gordon, Thumbi Ndung'u, and Jaclyn K. Mann. Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design. Virology, 554:1-8 doi, Feb 2021. PubMed ID: 33316731 Show all entries for this paper.


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