HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 11 matching records:

Displaying record number 59804

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol(160-167)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Species (MHC/HLA) human(B*1502)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59803

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol(160-167)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55090

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL-8
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Experimental methods  
Keywords escape, TCR usage, mutation acquisition

Notes

References

Yu2007 Xu G. Yu, Mathias Lichterfeld, Katie L. Williams, Javier Martinez-Picado, and Bruce D. Walker. Random T-Cell Receptor Recruitment in Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells from Genetically Identical Twins Infected with the Same HIV-1 Strain. J Virol, 81(22):12666-12669, Nov 2007. PubMed ID: 17804503. Show all entries for this paper.


Displaying record number 56036

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location RT
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8(RT)
Subtype B
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56393

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location RT(5-12)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Subtype B
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Country Australia, Canada, Germany, United States
Experimental methods  
Keywords HLA associated polymorphism

Notes

References

Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.


Displaying record number 59801

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol(160-167)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52566

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location RT(5-12)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Species (MHC/HLA) human(B*4001)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 55060

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol(160-167)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Show epitope variants
Epitope Name IL8
Species (MHC/HLA) human(B*4001)
Immunogen HIV-1 infection
Patient MHC/HLA A*0201, A*2402, B*4001, B*5001, Cw03, Cw4
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords immunodominance, escape, variant cross-reactivity

Notes

References

Draenert2006 Rika Draenert, Todd M. Allen, Yang Liu, Terri Wrin, Colombe Chappey, Cori L. Verrill, Guillem Sirera, Robert L. Eldridge, Matthew P. Lahaie, Lidia Ruiz, Bonaventura Clotet, Christos J. Petropoulos, Bruce D. Walker, and Javier Martinez-Picado. Constraints on HIV-1 Evolution and Immunodominance Revealed in Monozygotic Adult Twins Infected with the Same Virus. J. Exp. Med., 203(3):529-539, 20 Mar 2006. PubMed ID: 16533886. Show all entries for this paper.


Displaying record number 57322

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Subtype A, CRF02_AG, CRF06_cpx, CRF09_cpx
Species (MHC/HLA) human(B*60)
Immunogen HIV-1 infection
Country Burkina Faso
Experimental methods Other
Keywords drug resistance

Notes

References

Tebit2009 Denis M. Tebit, Lassana Sangaré, Fabrice Tiba, Yameogo Saydou, Aline Makamtse, Hermann Somlare, Guillaume Bado, Boris G. Kouldiaty, Inoussa Zabsonre, Sibiri L. Yameogo, Kanokporn Sathiandee, Joseph Y. Drabo, and Hans-Georg Kräusslich. Analysis of the Diversity of the HIV-1 pol Gene and Drug Resistance Associated Changes among Drug-Naïve Patients in Burkina Faso. J. Med. Virol., 81(10):1691-701, Oct 2009. PubMed ID: 19697403. Show all entries for this paper.


Displaying record number 59802

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location Pol(160-167)
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Species (MHC/HLA) human(C*17)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61801

HXB2 Location Pol(160-167)
RT(5-12)
DNA(2562..2585)
Pol Epitope Map
Author Location  
Epitope IETVPVKL Epitope Alignment
IETVPVKL epitope logo
Epitope Name IL8
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA VID406: A*0301, A*3101, B*4001, B*4403, Cw*0304, Cw*0401
Country United Kingdom
Experimental methods Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses, optimal epitope

Notes

References

Borthwick2017 Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, and Tomáš Hanke. Novel, In-Natural-Infection Subdominant HIV-1 CD8+ T-Cell Epitopes Revealed in Human Recipients of Conserved-Region T-Cell Vaccines. PLoS One, 12(4):1-19, 2017. PubMed ID: 28448594. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health