HIV molecular immunology database
Found 13 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(160-167) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Species (MHC/HLA) | human(B*15:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(160-167) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Species (MHC/HLA) | human(B*35:02, B*35:03, B*53:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(160-167) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | RT(5-12) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Subtype | B | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Country | Australia, Canada, Germany, United States | |
Experimental methods | ||
Keywords | HLA associated polymorphism |
Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL-8 | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | escape, TCR usage, mutation acquisition |
Yu2007 Xu G. Yu, Mathias Lichterfeld, Katie L. Williams, Javier Martinez-Picado, and Bruce D. Walker. Random T-Cell Receptor Recruitment in Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells from Genetically Identical Twins Infected with the Same HIV-1 Strain. J Virol, 81(22):12666-12669, Nov 2007. PubMed ID: 17804503. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8(RT) | |
Subtype | B | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | RT(5-12) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*40:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(160-167) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | IL8 | |
Species (MHC/HLA) | human(B*40:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*02:01, A*24:02, B*40:01, B*50:01, C*03, Cw4 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | immunodominance, escape, variant cross-reactivity |
Draenert2006 Rika Draenert, Todd M. Allen, Yang Liu, Terri Wrin, Colombe Chappey, Cori L. Verrill, Guillem Sirera, Robert L. Eldridge, Matthew P. Lahaie, Lidia Ruiz, Bonaventura Clotet, Christos J. Petropoulos, Bruce D. Walker, and Javier Martinez-Picado. Constraints on HIV-1 Evolution and Immunodominance Revealed in Monozygotic Adult Twins Infected with the Same Virus. J. Exp. Med., 203(3):529-539, 20 Mar 2006. PubMed ID: 16533886. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Subtype | A, CRF02_AG, CRF06_cpx, CRF09_cpx | |
Species (MHC/HLA) | human(B*60) | |
Immunogen | HIV-1 infection | |
Country | Burkina Faso | |
Experimental methods | Other | |
Keywords | drug resistance |
Tebit2009 Denis M. Tebit, Lassana Sangaré, Fabrice Tiba, Yameogo Saydou, Aline Makamtse, Hermann Somlare, Guillaume Bado, Boris G. Kouldiaty, Inoussa Zabsonre, Sibiri L. Yameogo, Kanokporn Sathiandee, Joseph Y. Drabo, and Hans-Georg Kräusslich. Analysis of the Diversity of the HIV-1 pol Gene and Drug Resistance Associated Changes among Drug-Naïve Patients in Burkina Faso. J. Med. Virol., 81(10):1691-701, Oct 2009. PubMed ID: 19697403. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(160-167) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Species (MHC/HLA) | human(C*17) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | ||
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL8 | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, vaccine | |
Patient MHC/HLA | VID406: A*03:01, A*31:01, B*40:01, B*44:03, C*03:04, C*04:01, DQB1*02, DQB1*05, DRB1*01:01, DRB1*07:01, DRB4 | |
Country | United Kingdom | |
Experimental methods | Intracellular cytokine staining, Other | |
Keywords | vaccine-induced immune responses, optimal epitope |
Borthwick2017 Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, and Tomáš Hanke. Novel, In-Natural-Infection Subdominant HIV-1 CD8+ T-Cell Epitopes Revealed in Human Recipients of Conserved-Region T-Cell Vaccines. PLoS One, 12(4):1-19, 2017. PubMed ID: 28448594. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) DNA(2562..2585) |
Pol Epitope Map |
---|---|---|
Author Location | RT(5-12) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Epitope Name | IL-8 | |
Subtype | B, C | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | acute/early infection, HLA associated polymorphism, chronic infection, protective allele |
Ojwach2018 Doty B. A. Ojwach, Daniel MacMillan, Tarylee Reddy, Vladimir Novitsky, Zabrina L. Brumme, Mark A. Brockman, Thumbi Ndung'u, and Jaclyn K. Mann. Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. J. Virol., 92(19), 1 Oct 2018. PubMed ID: 29997209. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(160-167) RT(5-12) |
Pol Epitope Map |
---|---|---|
Author Location | RT(5-12) | |
Epitope |
IETVPVKL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | IL8 | |
Subtype | B, C | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | vaccine antigen design |
Ojwach2021 Doty B. A. Ojwach, Paradise Madlala, Michelle Gordon, Thumbi Ndung'u, and Jaclyn K. Mann. Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design. Virology, 554:1-8 doi, Feb 2021. PubMed ID: 33316731 Show all entries for this paper.