HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 57278

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location RT
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Epitope Name IAW9
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Country Barbados, Haiti, Jamaica
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords mother-to-infant transmission, elite controllers

Notes

References

Schneidewind2009 Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, and Margaret E. Feeney. Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant. J. Virol., 83(17):8616-8627, Sep 2009. PubMed ID: 19515764. Show all entries for this paper.


Displaying record number 57424

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location  
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Show epitope variants
Epitope Name IAW9
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords elite controllers

Notes

References

Tang2010 Yanhua Tang, Sihong Huang, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, Elizabeth G. Ryland, M. Anne St. John, Rohan Hazra, Celia D. C. Christie, and Margaret E. Feeney. Correlates of Spontaneous Viral Control among Long-Term Survivors of Perinatal HIV-1 Infection Expressing Human Leukocyte Antigen-B57. AIDS, 24(10):1425-1435, 19 Jun 2010. PubMed ID: 20539088. Show all entries for this paper.


Displaying record number 55601

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location Pol
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Epitope Name IW9
Subtype B
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords computational epitope prediction

Notes

References

Schellens2008 Ingrid M. M. Schellens, Can Kesmir, Frank Miedema, Debbie van Baarle, and José A. M. Borghans. An Unanticipated Lack of Consensus Cytotoxic T Lymphocyte Epitopes in HIV-1 Databases: The Contribution of Prediction Programs. AIDS, 22(1):33-37, 2 Jan 2008. PubMed ID: 18090389. Show all entries for this paper.


Displaying record number 59381

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HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location Gag(162-172)
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Epitope Name IAW9
Subtype B, C
Species (MHC/HLA) human(B*57:01, B*57:03)
Immunogen HIV-1 infection
Country Barbados, Botswana, Spain, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Relative replication capacity assay, TCR binding
Keywords subtype comparisons, variant cross-reactivity

Notes

References

Payne2014 R. P. Payne, S. Branch, H Kløverpris, P. C. Matthews, C. K. Koofhethile, T. Strong, E. Adland, E. Leitman, J. Frater, T. Ndung'u, E. Hunter, R. Haubrich, B. Mothe, A. Edwards, L. Riddell, F. Chen, P. R. Harrigan, Z. L. Brumme, S. Mallal, M. John, J. P. Jooste, R. Shapiro, S. G. Deeks, B. D. Walker, C. Brander, C. Landis, J. M. Carlson, J. G. Prado, and P. J. R. Goulder. Differential Escape Patterns within the Dominant HLA-B*57:03-Restricted HIV Gag Epitope Reflect Distinct Clade-Specific Functional Constraints. J. Virol., 88(9):4668-4678, May 2014. PubMed ID: 24501417. Show all entries for this paper.


Displaying record number 56053

Download this epitope record as JSON.

HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location RT
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Show epitope variants
Epitope Name IW9(RT)
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56973

Download this epitope record as JSON.

HXB2 Location Pol(530-538)
RT(375-383)
DNA(3672..3698)
Pol Epitope Map
Author Location Pol
Epitope IATESIVIW Epitope Alignment
IATESIVIW epitope logo
Subtype B, D
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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