HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 55677

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HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location Gag
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity

Notes

References

Chopera2008 Denis R. Chopera, Zenda Woodman, Koleka Mlisana, Mandla Mlotshwa, Darren P. Martin, Cathal Seoighe, Florette Treurnicht, Debra Assis de Rosa, Winston Hide, Salim Abdool Karim, Clive M. Gray, Carolyn Williamson, and CAPRISA 002 Study Team. Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage. PLoS Pathog, 4(3):e1000033, Mar 2008. PubMed ID: 18369479. Show all entries for this paper.


Displaying record number 57694

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HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location p17
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*23:01, A*23:01, B*08:01, B*15:10, C*07:01, C*16:01; A*23:01, A*29:02, B*42:02, B*44:03, C*17:01, C*17:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, acute/early infection

Notes

References

Mlotshwa2010 Mandla Mlotshwa, Catherine Riou, Denis Chopera, Debra de Assis Rosa, Roman Ntale, Florette Treunicht, Zenda Woodman, Lise Werner, Francois van Loggerenberg, Koleka Mlisana, Salim Abdool Karim, Carolyn Williamson, Clive M Gray, and CAPRISA 002 Study Team. Fluidity of HIV-1-Specific T-Cell Responses during Acute and Early Subtype C HIV-1 Infection and Associations with Early Disease Progression. J. Virol., 84(22):12018-12029, Nov 2010. PubMed ID: 20826686. Show all entries for this paper.


Displaying record number 53278

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HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location ( C consensus)
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01, A*24:02)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HLA cross-presentation, characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 56245

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HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location  
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype C
Species (MHC/HLA) human(A*23:01, A*24:02)
Immunogen HIV-1 infection
Patient MHC/HLA A*23:01, B*08:01, B*15:10, C*07:01, C*16:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords rate of progression

Notes

References

Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.


Displaying record number 54174

Download this epitope record as JSON.

HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location (28-36)
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype C
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection
Experimental methods Other
Keywords HLA associated polymorphism

Notes

References

Boutwell2007 Christian L. Boutwell and M. Essex. Identification of HLA Class I-Associated Amino Acid Polymorphisms in the HIV-1C Proteome. AIDS Res. Hum. Retroviruses, 23(1):165-174, Jan 2007. PubMed ID: 17263647. Show all entries for this paper.


Displaying record number 55475

Download this epitope record as JSON.

HXB2 Location Gag(28-36)
p17(28-36)
DNA(871..897)
Gag Epitope Map
Author Location Gag
Epitope HYMLKHLVW Epitope Alignment
HYMLKHLVW epitope logo
Subtype A1, B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, variant cross-reactivity, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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