HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 62468

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HXB2 Location gp160(769-777)
gp41(258-266)
DNA(8529..8555)
gp160 Epitope Map
Author Location Env
Epitope HRLRDLLLI Epitope Alignment
HRLRDLLLI epitope logo
Epitope Name HI9
Subtype B
Species (MHC/HLA) human(B*27:02)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Other, Tetramer binding
Keywords immunodominance, chronic infection, protective allele

Notes

References

Adland2018 Emily Adland, Matilda Hill, Nora Lavandier, Anna Csala, Anne Edwards, Fabian Chen, Marek Radkowski, Justyna D. Kowalska, Dimitrios Paraskevis, Angelos Hatzakis, Humberto Valenzuela-Ponce, Katja Pfafferott, Ian Williams, Pierre Pellegrino, Persephone Borrow, Masahiko Mori, Jürgen Rockstroh, Julia G. Prado, Beatriz Mothe, Judith Dalmau, Javier Martinez-Picado, Gareth Tudor-Williams, John Frater, Anette Stryhn, Soren Buus, Gustavo Reyes Teran, Simon Mallal, Mina John, Susan Buchbinder, Gregory Kirk, Jeffrey Martin, Nelson Michael, Jacques Fellay, Steve Deeks, Bruce Walker, Santiago Avila-Rios, David Cole, Christian Brander, Mary Carrington, and Philip Goulder. Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J. Virol., 92(4), 15 Feb 2018. PubMed ID: 29167337. Show all entries for this paper.


Displaying record number 62481

Download this epitope record as JSON.

HXB2 Location gp160(769-777)
gp41(258-266)
DNA(8529..8555)
gp160 Epitope Map
Author Location Env
Epitope HRLRDLLLI Epitope Alignment
HRLRDLLLI epitope logo
Epitope Name HI9
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Other, Tetramer binding
Keywords immunodominance, chronic infection, protective allele

Notes

References

Adland2018 Emily Adland, Matilda Hill, Nora Lavandier, Anna Csala, Anne Edwards, Fabian Chen, Marek Radkowski, Justyna D. Kowalska, Dimitrios Paraskevis, Angelos Hatzakis, Humberto Valenzuela-Ponce, Katja Pfafferott, Ian Williams, Pierre Pellegrino, Persephone Borrow, Masahiko Mori, Jürgen Rockstroh, Julia G. Prado, Beatriz Mothe, Judith Dalmau, Javier Martinez-Picado, Gareth Tudor-Williams, John Frater, Anette Stryhn, Soren Buus, Gustavo Reyes Teran, Simon Mallal, Mina John, Susan Buchbinder, Gregory Kirk, Jeffrey Martin, Nelson Michael, Jacques Fellay, Steve Deeks, Bruce Walker, Santiago Avila-Rios, David Cole, Christian Brander, Mary Carrington, and Philip Goulder. Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J. Virol., 92(4), 15 Feb 2018. PubMed ID: 29167337. Show all entries for this paper.


Displaying record number 862

Download this epitope record as JSON.

HXB2 Location gp160(769-777)
gp41(258-266)
DNA(8529..8555)
gp160 Epitope Map
Author Location gp41(769-777 BH10)
Epitope HRLRDLLLI Epitope Alignment
HRLRDLLLI epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Safrit1994a J. T. Safrit, C. A. Andrews, T. Zhu, D. D. Ho, and R. A. Koup. Characterization of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocyte Clones Isolated during Acute Seroconversion: Recognition of Autologous Virus Sequences within a Conserved Immunodominant Epitope. J. Exp. Med., 179:463-472, 1994. HIV-1 specific CTL clones were isolated from two individuals at acute seroconversion. In one patient, two HLA A31-restricted clones recognized the same fragment of gp41, peptide RLRDLLLIVTR, but one was sensitive to a Thr to Val substitution, while the other was not. A CTL HLA A32-restricted clone from the other patient recognized the gp41 peptide VLSIVNRVRQGYSPLSFQTH. Autologous viral sequences from seroconversion were recognized by the CTL clones, but not the HIV-1 strain MN. PubMed ID: 8294860. Show all entries for this paper.


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