HIV molecular immunology database
Found 12 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL9 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | p24(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*15) | |
Immunogen | HIV-1 infection | |
Country | Australia, Canada, Germany, United States | |
Experimental methods | ||
Keywords | HLA associated polymorphism |
Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | p24(144-152 NL4-3) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*15) | |
Immunogen | computer prediction | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | vaccine antigen design, viral fitness and reversion |
Ferguson2013a Andrew L. Ferguson, Jaclyn K. Mann, Saleha Omarjee, Thumbi Ndung'u, Bruce D Walker, and Arup K. Chakraborty. Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design. Immunity, 38(3):606-617, 21 Mar 2013. PubMed ID: 23521886. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | p24(12-20 NL4.3) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*15) | |
Immunogen | HIV-1 infection | |
Experimental methods | In vitro proteasome digestion, Other | |
Keywords | epitope processing |
Kourjian2014 Georgio Kourjian, Yang Xu, Ijah Mondesire-Crump, Mariko Shimada, Pauline Gourdain, and Sylvie Le Gall. Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors. J. Immunol., 192(8):3496-3506, 15 Apr 2014. PubMed ID: 24616479. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | p24(12-20) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL-9 | |
Subtype | B, C | |
Species (MHC/HLA) | human(B*15:10) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*15:10) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL9 | |
Species (MHC/HLA) | human(B*39) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL9 | |
Species (MHC/HLA) | human(B*42:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Epitope Name | HL9 | |
Species (MHC/HLA) | human(C*06) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(146-154) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Species (MHC/HLA) | chimpanzee(Patr-B*02) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Balla1999b S. S. Balla-Jhagjhoorsingh, G. Koopman, P. Mooij, T. G. Haaksma, V. J. Teeuwsen, R. E. Bontrop, and J. L. Heeney. Conserved CTL epitopes shared between HIV-infected human long-term survivors and chimpanzees. J. Immunol., 162:2308-14, 1999. PubMed ID: 9973508. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | Gag | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | vaccine | |
Patient MHC/HLA | A*02:01, A*24:02, B*14:02, B*39:01, C*08:02, C*12:03; A*02:01, A*03:01, B*07:02, B*39:01, C*07:02, C*12:03 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | vaccine-induced immune responses |
Vaccine type | adenovirus type 5 (Ad5), DNA prime with Ad5 boost |
---|---|
Vaccine strain | B clade IIIB, B clade JRFL, B clade CAM-1 |
Vaccine component | Gag, Nef, Pol |
Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(144-152) p24(12-20) DNA(1219..1245) |
Gag Epitope Map |
---|---|---|
Author Location | p24(144-152) | |
Epitope |
HQAISPRTL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.