HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 52829

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HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location p24(84-92)
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Epitope Name B7-HA9 Gag
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supervised treatment interruptions (STI), escape, early treatment, superinfection

Notes

References

Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.


Displaying record number 53371

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HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location ( B consensus)
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Epitope Name HA9
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B7, Cw7
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 55874

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HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location Gag
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons

Notes

References

Gudmundsdotter2008 L. Gudmundsdotter, D. Bernasconi, B. Hejdeman, E. Sandstrom, A. Alaeus, K. Lidman, B. Ensoli, B. Wahren, and S. Buttò. Cross-Clade Immune Responses to Gag p24 in Patients Infected with Different HIV-1 Subtypes and Correlation with HLA Class I and II Alleles. Vaccine, 26(40):5182-5187, 19 Sep 2008. PubMed ID: 18479789. Show all entries for this paper.


Displaying record number 56088

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HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location Gag
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Epitope Name Gag1156
Subtype C
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, computational epitope prediction, HLA associated polymorphism

Notes

References

DeGroot2008 Anne S. De Groot, Daniel S. Rivera, Julie A. McMurry, Soren Buus, and William Martin. Identification of Immunogenic HLA-B7 ``Achilles' Heel'' Epitopes within Highly Conserved Regions of HIV. Vaccine, 26(24):3059-3071, 6 Jun 2008. PubMed ID: 18206276. Show all entries for this paper.


Displaying record number 57432

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HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location p24(84-92)
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Show epitope variants
Epitope Name HA9
Subtype A1, C, D
Species (MHC/HLA) human(B7 supertype)
Immunogen HIV-1 infection
Country Sweden, Uganda
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity

Notes

References

Hoof2010 Ilka Hoof, Carina L. Pérez, Marcus Buggert, Rasmus K. L. Gustafsson, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Interdisciplinary Analysis of HIV-Specific CD8+ T Cell Responses against Variant Epitopes Reveals Restricted TCR Promiscuity. J Immunol, 184(9):5383-5391, 1 May 2010. PubMed ID: 20363973. Show all entries for this paper.


Displaying record number 55477

Download this epitope record as JSON.

HXB2 Location Gag(216-224)
p24(84-92)
DNA(1435..1461)
Gag Epitope Map
Author Location Gag
Epitope HPVHAGPVA Epitope Alignment
HPVHAGPVA epitope logo
Subtype A1, B, C, D
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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