HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 62211

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HXB2 Location Pol(886-895)
Integrase(171-180)
DNA(4740..4769)
Pol Epitope Map
Author Location Integrase(171-180)
Epitope HLKTAVQMAV Epitope Alignment
HLKTAVQMAV epitope logo
Epitope Name HV10
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection, vaccine
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, therapeutic vaccine

Vaccine Details

Vaccine type DNA prime with Ad5 boost
Vaccine strain A clade, B clade, C clade
Vaccine component Env, Gag, Nef, Pol

Notes

References

Casazza2013 Joseph P. Casazza, Kathryn A. Bowman, Selorm Adzaku, Emily C. Smith, Mary E. Enama, Robert T. Bailer, David A. Price, Emma Gostick, Ingelise J. Gordon, David R. Ambrozak, Martha C. Nason, Mario Roederer, Charla A. Andrews, Frank M. Maldarelli, Ann Wiegand, Mary F. Kearney, Deborah Persaud, Carrie Ziemniak, Raphael Gottardo, Julie E. Ledgerwood, Barney S. Graham, Richard A. Koup, and VRC 101 Study Team. Therapeutic Vaccination Expands and Improves the Function of the HIV-Specific Memory T-Cell Repertoire. J. Infect. Dis., 207(12):1829-1840, 15 Jun 2013. PubMed ID: 23482645. Show all entries for this paper.


Displaying record number 52858

Download this epitope record as JSON.

HXB2 Location Pol(886-895)
Integrase(171-180)
DNA(4740..4769)
Pol Epitope Map
Author Location Pol
Epitope HLKTAVQMAV Epitope Alignment
HLKTAVQMAV epitope logo
Epitope Name 1247
Subtype multiple
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Patient MHC/HLA H0014M: A*01, A*02, B*08
Experimental methods T-cell Elispot
Keywords binding affinity, computational epitope prediction, novel epitope

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


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