HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 771

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HXB2 Location gp160(314-322)
gp120(314-322)
DNA(7164..7190)
gp160 Epitope Map
Author Location gp120(314-322)
Epitope GRAFVTIGK Epitope Alignment
GRAFVTIGK epitope logo
Species (MHC/HLA) human(B27)
Immunogen peptide-HLA interaction
Experimental methods  
Keywords  

Notes

References

Jardetzky1991 T. S. Jardetzky, W. S. Lane, R. A. Robinson, D. R. Madden, and D. C. Wiley. Identification of Self Peptides Bound to Purified HLA-B27. Nature, 353:326-329, 1991. A pool of endogenous peptides bound to the human class I MHC molecule, HLA-B27, has been isolated. Microsequence analysis of the pool and of 11 HPLC-purified peptides provides information on the binding specificity of the HLA-B27 molecule. The peptides all seem to be nonamers, seven of which match to protein sequences in a database search. These self peptides derive from abundant cytosolic or nuclear proteins, such as histone, ribosomal proteins, and members of the 90K heat-shock protein family. PubMed ID: 1922338. Show all entries for this paper.


Displaying record number 53014

Download this epitope record as JSON.

HXB2 Location gp160(314-322)
gp120(314-322)
DNA(7164..7190)
gp160 Epitope Map
Author Location gp120(312-320)
Epitope GRAFVTIGK Epitope Alignment
GRAFVTIGK epitope logo
Subtype B
Species (MHC/HLA) human(B*27:05)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, CD8 T-cell Elispot granzyme B
Keywords Th1, characterizing CD8+ T cells

Notes

References

Kleen2004 Thomas O. Kleen, Robert Asaad, Samuel J. Landry, Bernhard O. Boehm, and Magdalena Tary-Lehmann. Tc1 Effector Diversity Shows Dissociated Expression of Granzyme B and Interferon-gamma in HIV Infection. AIDS, 18(3):383-392, 20 Feb 2004. PubMed ID: 15090789. Show all entries for this paper.


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