HIV molecular immunology database
Found 7 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
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Author Location | Pol(488-496) | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Epitope Name | GI9 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(488-496) | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*03:01, A*30:01, B*13:01, B*14:02, C*06:02, C*08:02 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | epitope processing, escape, mutation acquisition, viral fitness and reversion, HLA associated polymorphism |
Honeyborne2007 Isobella Honeyborne, Andrew Prendergast, Florencia Pereyra, Alasdair Leslie, Hayley Crawford, Rebecca Payne, Shabashini Reddy, Karen Bishop, Eshia Moodley, Kriebashnie Nair, Mary van der Stok, Noel McCarthy, Christine M. Rousseau, Marylyn Addo, James I. Mullins, Christian Brander, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder. Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8+ T-Cell Epitopes. J. Virol., 81(7):3667-3672, Apr 2007. PubMed ID: 17251285. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
---|---|---|
Author Location | ||
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Epitope Name | GI9 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(488-496) | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Epitope Name | GI9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | S00024: A*02, B*13, B*15, C*06, C*07; S00039: A*31, A*32, B*13, B*35, C*04, C*06 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | dynamics, chronic infection |
Balamurugan2017 Arumugam Balamurugan, Deon Claiborne, Hwee L. Ng, and Otto O. Yang. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth. J. Virol., 91(16), 15 Aug 2017. PubMed ID: 28592539. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
---|---|---|
Author Location | RT | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Epitope Name | GI9(RT) | |
Subtype | B | |
Species (MHC/HLA) | human(B13) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) DNA(3546..3572) |
Pol Epitope Map |
---|---|---|
Author Location | RT(333-341) | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | GI9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | Relative replication capacity assay | |
Keywords | class I down-regulation by Nef, escape, novel epitope |
Shahid2015 Aniqa Shahid, Alex Olvera, Gursev Anmole, Xiaomei T. Kuang, Laura A. Cotton, Montserrat Plana, Christian Brander, Mark A. Brockman, and Zabrina L. Brumme. Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function. J. Virol., 89(22):11557-11571, Nov 2015. PubMed ID: 26355081. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(488-496) RT(333-341) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
GQGQWTYQI
|
Epitope Alignment
|
Show epitope variants | ||
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, vaccine | |
Patient MHC/HLA | PubID 5050122: A*30, B*13:02; PubID 5051958: A*30, B*13:02; PubID 5051993: B*13:02 | |
Experimental methods | Other | |
Keywords | vaccine-induced immune responses, variant cross-reactivity |
Vaccine type | DNA, polyepitope, adenovirus type 5 (Ad5), recombinant protein |
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Vaccine component | Env, Gag, Nef, Pol |
Boppana2020 Sushma Boppana, Andrew Fiore-Gartland, Anju Bansal, and Paul Goepfert. Cross-Reactive CD8 T-Cell Responses Elicited by Adenovirus Type 5-Based HIV-1 Vaccines Contributed to Early Viral Evolution in Vaccine Recipients Who Became Infected. J Virol, 94(2):JVI01632-19 doi, Jan 2020. PubMed ID: 31645444 Show all entries for this paper.