HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 26 matching records:

Displaying record number 59732

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(173-181)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(B*08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57326

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype A, CRF02_AG, CRF06_cpx, CRF09_cpx
Species (MHC/HLA) human(B*08)
Immunogen HIV-1 infection
Country Burkina Faso
Experimental methods Other
Keywords drug resistance

Notes

References

Tebit2009 Denis M. Tebit, Lassana Sangaré, Fabrice Tiba, Yameogo Saydou, Aline Makamtse, Hermann Somlare, Guillaume Bado, Boris G. Kouldiaty, Inoussa Zabsonre, Sibiri L. Yameogo, Kanokporn Sathiandee, Joseph Y. Drabo, and Hans-Georg Kräusslich. Analysis of the Diversity of the HIV-1 pol Gene and Drug Resistance Associated Changes among Drug-Naïve Patients in Burkina Faso. J. Med. Virol., 81(10):1691-701, Oct 2009. PubMed ID: 19697403. Show all entries for this paper.


Displaying record number 1798

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) human(B*08)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 54324

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) human(B*0801)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other
Keywords vaccine-induced immune responses, HLA cross-presentation, HLA associated polymorphism

Notes

References

Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.


Displaying record number 406

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193 LAI)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B*0801)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61627

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name B*08-GL9
Subtype C
Species (MHC/HLA) human(B*0801)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords elite controllers

Notes

References

Koofhethile2016 Catherine K. Koofhethile, Zaza M. Ndhlovu, Christina Thobakgale-Tshabalala, Julia G. Prado, Nasreen Ismail, Zenele Mncube, Lungile Mkhize, Mary van der Stok, Nonhlanhla Yende, Bruce D. Walker, Philip J. R. Goulder, and Thumbi Ndung'u. CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. J. Virol., 90(15):6818-6831, 1 Aug 2016. PubMed ID: 27194762. Show all entries for this paper.


Displaying record number 60946

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B*0801)
Immunogen HIV-1 infection
Patient MHC/HLA 44149: A*0101, A*2401, B*0701, B*0801, Cw*0701, Cw*0702
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 59733

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(173-181)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(B*4202)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 58717

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name RT-GL9
Subtype C
Species (MHC/HLA) human(B*4202)
Immunogen HIV-1 infection
Patient MHC/HLA A*3001, B*4202, Cw*1701
Country Botswana, South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HLA associated polymorphism, novel epitope

Notes

References

Kloverpris2012a Henrik N. Kløverpris, Mikkel Harndahl, Alasdair J. Leslie, Jonathan M. Carlson, Nasreen Ismail, Mary van der Stok, Kuan-Hsiang Gary Huang, Fabian Chen, Lynn Riddell, Dewald Steyn, Dominique Goedhals, Cloete van Vuuren, John Frater, Bruce D. Walker, Mary Carrington, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HIV Control through a Single Nucleotide on the HLA-B Locus. J. Virol., 86(21):11493-11500, Nov 2012. PubMed ID: 22896606. Show all entries for this paper.


Displaying record number 55502

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location p24
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GL9
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding
Keywords characterizing CD8+ T cells

Notes

References

Streeck2008 Hendrik Streeck, Zabrina L. Brumme, Michael Anastario, Kristin W. Cohen, Jonathan S. Jolin, Angela Meier, Chanson J. Brumme, Eric S. Rosenberg, Galit Alter, Todd M. Allen, Bruce D. Walker, and Marcus Altfeld. Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1-Specific CD8+ T Cells. PLoS Med, 5(5):e100, 6 May 2008. PubMed ID: 18462013. Show all entries for this paper.


Displaying record number 53023

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(171-180)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, CD8 T-cell Elispot granzyme B
Keywords Th1, characterizing CD8+ T cells

Notes

References

Kleen2004 Thomas O. Kleen, Robert Asaad, Samuel J. Landry, Bernhard O. Boehm, and Magdalena Tary-Lehmann. Tc1 Effector Diversity Shows Dissociated Expression of Granzyme B and Interferon-gamma in HIV Infection. AIDS, 18(3):383-392, 20 Feb 2004. PubMed ID: 15090789. Show all entries for this paper.


Displaying record number 403

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Show epitope variants
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Meier1995 U.-C. Meier, P. Klenerman, P. Griffin, W. James, B. Koppe, B. Larder, R. E. Phillips, A. J. McMichael, and R. E. Phillips. Cytotoxic T Lymphocyte Lysis Inhibited by Viable HIV Mutants. Science, 270:1360-1362, 1995. HIV bearing mutations in epitope allowed transactive inhibition of specific CTL mediated lysis. Therefore, mutations in epitopes may not only allow escape from specific CTL, but enhance the ability of wildtype virus to persist. PubMed ID: 7481824. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 53751

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(173-181)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Show epitope variants
Epitope Name GL9
Subtype B
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Patient MHC/HLA A*01, A*11, B*08, B*15, Cw*04, Cw*07
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords escape, variant cross-reactivity, optimal epitope

Notes

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.


Displaying record number 54340

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name B8-GL9(RT)
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 54808

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location  
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) (B8)
Immunogen  
Experimental methods  
Keywords review, immunodominance, escape, vaccine antigen design

Notes

References

Altfeld2006a Marcus Altfeld and Todd M. Allen. Hitting HIV Where It Hurts: An Alternative Approach to HIV Vaccine Design. Trends Immunol., 27(11):504-510, Nov 2006. PubMed ID: 16997629. Show all entries for this paper.


Displaying record number 53376

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location ( B consensus)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GL9
Subtype B
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Patient MHC/HLA A25, A32, B14, B8, Cw7, Cw8
Country United States
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 404

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(173-181)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Show epitope variants
Species (MHC/HLA) human(B8)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Goulder1997c P. J. R. Goulder, S. W. Reid, D. A. Price, C. A. O'Callaghan, A. J. McMichael, R. E. Phillips, and E. Y. Jones. Combined Structural and Immunological Refinement of HIV-1 HLA-B8 Restricted Cytotoxic T Lymphocyte Epitopes. Eur. J. Immunol., 27:1515-1521, 1997. PubMed ID: 9209505. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 405

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193 LAI)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B8)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Sutton1993 J. Sutton, S. Rowland-Jones, W. Rosenberg, D. Nixon, F. Gotch, X.-M. Gao, N. Murray, A. Spoonas, P. Driscoll, M. Smith, A. Willis, and A. McMichael. A Sequence Pattern for Peptides Presented to Cytotoxic T Lymphocytes by HLA B8 Revealed by Analysis of Epitopes and Eluted Peptides. Eur. J. Immunol., 23:447-453, 1993. PubMed ID: 7679646. Show all entries for this paper.


Displaying record number 407

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193 LAI)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Klenerman1995 P. Klenerman, U.-C. Meier, R. E. Phillips, and A. J. McMichael. The Effects of Natural Altered Peptide Ligands on the Whole Blood Cytotoxic T Lymphocyte Response to Human Immunodeficiency Virus. Eur. J. Immunol., 25:1927-1931, 1995. This paper explores naturally occurring altered peptide ligands and their ability to sustain CTL, serve as antagonists to CTL specific for other variants, and to allow cell killing. The authors propose that a CTL response may be sustained in vivo that fails to recognize viral variants as they arise, proposing a mechanism for T-cell original antigenic sin. PubMed ID: 7542596. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 408

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(18-26)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) human(B8)
Immunogen in vitro stimulation or selection
Experimental methods  
Keywords dendritic cells

Notes

References

Zarling1999 A. L. Zarling, J. G. Johnson, R. W. Hoffman, and D. R. Lee. Induction of Primary Human CD8+ T Lymphocyte Responses In Vitro Using Dendritic Cells. J. Immunol., 162:5197-5204, 1999. PubMed ID: 10227993. Show all entries for this paper.


Displaying record number 1377

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GPK
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, supervised treatment interruptions (STI), immunodominance, escape, acute/early infection

Notes

References

Oxenius2000b A. Oxenius, D. A. Price, P. J. Easterbrook, C. A. O'Callaghan, A. D. Kelleher, J. A. Whelan, G. Sontag, A. K. Sewell, and R. E. Phillips. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc. Natl. Acad. Sci. U.S.A., 97(7):3382-7, 28 Mar 2000. URL: http://www.pnas.org/cgi/content/full/97/7/3382. PubMed ID: 10737796. Show all entries for this paper.


Displaying record number 1485

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART

Notes

References

Seth2001 A. Seth, J. Markee, A. Hoering, A. Sevin, D. E. Sabath, J. E. Schmitz, M. J. Kuroda, M. A. Lifton, M. S. Hirsch, A. C. Collier, N. L. Letvin, and M. J. McElrath. Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy. J. Infect. Dis., 183(5):722-9, 1 Mar 2001. PubMed ID: 11181148. Show all entries for this paper.


Displaying record number 1576

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193 SF2)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 1672

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(171-180)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype A, B, C, D
Species (MHC/HLA) human(B8)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 52322

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GPK
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Oxenius2002b Annette Oxenius, Angela R. McLean, Marek Fischer, David A. Price, Sarah J. Dawson, Roland Hafner, Christine Schneider, Helen Joller, Bernard Hirschel, Rodney E. Phillips, Rainer Weber, Huldrych F. Günthard, and Swiss HIV Cohort Study Group. Human Immunodeficiency Virus-Specific CD8+ T-Cell Responses Do Not Predict Viral Growth and Clearance Rates During Structured Intermittent Antiretroviral Therapy. J. Virol., 76(20):10169-10176, Oct 2002. PubMed ID: 12239291. Show all entries for this paper.


Displaying record number 59734

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location Pol(173-181)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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