HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 31 matching records:

Displaying record number 55877

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype A, B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons

Notes

References

Gudmundsdotter2008 L. Gudmundsdotter, D. Bernasconi, B. Hejdeman, E. Sandstrom, A. Alaeus, K. Lidman, B. Ensoli, B. Wahren, and S. Buttò. Cross-Clade Immune Responses to Gag p24 in Patients Infected with Different HIV-1 Subtypes and Correlation with HLA Class I and II Alleles. Vaccine, 26(40):5182-5187, 19 Sep 2008. PubMed ID: 18479789. Show all entries for this paper.


Displaying record number 56299

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(269-277 SF2, HXBc2/Bal R5)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A3, B15, B7, Cw3, Cw6
Country United States
Experimental methods Cytokine production, Degranulation, CD107a and b cell surface mobilization, Flow cytometric T-cell cytokine assay
Keywords supervised treatment interruptions (STI), immunodominance, characterizing CD8+ T cells, drug resistance

Notes

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


Displaying record number 52926

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag( B con)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity

Notes

References

Draenert2004b R. Draenert, C. L. Verrill, Y. Tang, T. M. Allen, A. G. Wurcel, M. Boczanowski, A. Lechner, A. Y. Kim, T. Suscovich, N. V. Brown, M. M. Addo, and B. D. Walker. Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(2):630-641, Jan 2004. PubMed ID: 14694094. Show all entries for this paper.


Displaying record number 54345

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name B15-GY9(p24)
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 55994

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9(p24)
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 54529

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(137-145)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B15, B62)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, subtype comparisons, acute/early infection

Notes

References

Malhotra2007 Uma Malhotra, Jessica Nolin, James I. Mullins, and M. Juliana McElrath. Comprehensive Epitope Analysis of Cross-Clade Gag-Specific T-Cell Responses in Individuals with Early HIV-1 Infection in the US Epidemic. Vaccine, 25(2):381-390, 4 Jan 2007. PubMed ID: 17112643. Show all entries for this paper.


Displaying record number 58278

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location  
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining, Tetramer binding
Keywords variant cross-reactivity, characterizing CD8+ T cells

Notes

References

Conrad2011 Joseph A. Conrad, Ramesh K. Ramalingam, Rita M. Smith, Louise Barnett, Shelly L. Lorey, Jie Wei, Brenna C. Simons, Shanmugalakshmi Sadagopal, Dirk Meyer-Olson, and Spyros A. Kalams. Dominant Clonotypes within HIV-Specific T Cell Responses Are Programmed Death-1 High and CD127 Low and Display Reduced Variant Cross-Reactivity. J. Immunol., 186(12):6871-6885, 15 Jun 2011. PubMed ID: 21562156. Show all entries for this paper.


Displaying record number 58550

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name B15-GY9
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Country United States
Experimental methods  
Keywords review, rate of progression, acute/early infection

Notes

References

Streeck2010 Hendrik Streeck and Douglas F. Nixon. T Cell Immunity in Acute HIV-1 Infection. J. Infect. Dis., 202(Suppl 2):S302-8, 15 Oct 2010. PubMed ID: 20846037. Show all entries for this paper.


Displaying record number 58801

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location  
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name B*15-GY9
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Country United States
Experimental methods Other, Tetramer binding
Keywords  

Notes

References

Conrad2012 Joseph A. Conrad, Ramesh K. Ramalingam, Coley B. Duncan, Rita M. Smith, Jie Wei, Louise Barnett, Brenna C. Simons, Shelly L. Lorey, and Spyros A. Kalams. Antiretroviral Therapy Reduces the Magnitude and T Cell Receptor Repertoire Diversity of HIV-Specific T Cell Responses without Changing T Cell Clonotype Dominance. J. Virol., 86(8):4213-4221, Apr 2012. PubMed ID: 22258246. Show all entries for this paper.


Displaying record number 57384

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(240-249)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection, in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 60688

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B*15)
Immunogen HIV-1 infection
Patient MHC/HLA S3:
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dendritic cells, assay or method development, memory cells

Notes

References

Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.


Displaying record number 61775

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location  
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Subtype B
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication, Intracellular cytokine staining
Keywords vaccine-induced immune responses, variant cross-reactivity

Notes

References

Murakoshi2018 Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. CD8+ T Cells Specific for Conserved, Cross-Reactive Gag Epitopes with Strong Ability to Suppress HIV-1 Replication. Retrovirology, 15(1):46, 3 Jul 2018. PubMed ID: 29970102. Show all entries for this paper.


Displaying record number 302

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(272-280 LAI)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 53245

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277 SUMA)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name Gag GY9
Subtype B
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Patient MHC/HLA A*1103, A*2402, B*1402, B*1501, Cw*0802
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords dynamics, acute/early infection, characterizing CD8+ T cells

Notes

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.


Displaying record number 54326

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(137-145)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other
Keywords vaccine-induced immune responses, HLA cross-presentation, HLA associated polymorphism

Notes

References

Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.


Displaying record number 55034

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location  
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 57074

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(137-145 DU422)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B*1501)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 59728

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54882

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location  
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection, vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords vaccine-induced immune responses, characterizing CD8+ T cells

Vaccine Details

Vaccine type canarypox, canarypox prime with recombinant protein boost
Vaccine strain B clade BRU, B clade LAI, B clade MN, multiple epitope immunogen
Vaccine component Gag, gp120, gp41, Nef, Pol, Protease

Notes

References

Horton2006 Helen Horton, Ian Frank, Ruth Baydo, Emilie Jalbert, Justin Penn, Sean Wilson, John P. McNevin, Matthew D. McSweyn, Deborah Lee, Yunda Huang, Stephen C. De Rosa, and M. Juliana McElrath. Preservation of T Cell Proliferation Restricted by Protective HLA Alleles Is Critical for Immune Control of HIV-1 Infection. J. Immunol., 177(10):7406-7415, 15 Nov 2006. PubMed ID: 17082660. Show all entries for this paper.


Displaying record number 59729

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52645

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(137-145)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A3, B62, B8, Cw3, Cw7
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 1551

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(267-277 SF2)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 52750

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A24, B27, B62
Experimental methods Chromium-release assay
Keywords TCR usage, genital and mucosal immunity

Notes

References

Musey2003 L. Musey, Y. Ding, J. Cao, J. Lee, C. Galloway, A. Yuen, K. R. Jerome, and M. J. McElrath. Ontogeny and Specificities of Mucosal and Blood Human Immunodeficiency Virus Type 1-Specific CD8+ Cytotoxic T Lymphocytes. J. Virol., 77(1):291-300, Jan 2003. PubMed ID: 12477834. Show all entries for this paper.


Displaying record number 1179

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24( SF2)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons, immunodominance

Notes

References

Goulder2000 P. J. Goulder, C. Brander, K. Annamalai, N. Mngqundaniso, U. Govender, Y. Tang, S. He, K. E. Hartman, C. A. O'Callaghan, G. S. Ogg, M. A. Altfeld, E. S. Rosenberg, H. Cao, S. A. Kalams, M. Hammond, M. Bunce, S. I. Pelton, S. A. Burchett, K. McIntosh, H. M. Coovadia, and B. D. Walker. Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children. J. Virol., 74:5679-90, 2000. PubMed ID: 10823876. Show all entries for this paper.


Displaying record number 301

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(272-280 LAI)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype B
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Experimental methods  
Keywords review, escape

Notes

References

Goulder1997e P. Goulder, D. Price, M. Nowak, S. Rowland-Jones, R. Phillips, and A. McMichael. Co-Evolution of Human Immunodeficiency Virus and Cytotoxic T-Lymphocyte Responses. Immunol. Rev., 159:17-29, 1997. PubMed ID: 9416500. Show all entries for this paper.


Displaying record number 53750

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Subtype B
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Patient MHC/HLA A*01, A*11, B*08, B*15, Cw*04, Cw*07
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords escape, optimal epitope

Notes

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.


Displaying record number 1815

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24(137-145)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B*62)
Immunogen HIV-1 infection
Experimental methods  
Keywords immunodominance

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 58611

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24( SF2)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human(B*62)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 59730

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag(269-277)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Epitope Name GY9
Species (MHC/HLA) human(C*01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1182

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location p24( C consensus)
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A2, B*5802, B62, Cw4, Cw6
Experimental methods  
Keywords subtype comparisons, immunodominance

Notes

References

Goulder2000 P. J. Goulder, C. Brander, K. Annamalai, N. Mngqundaniso, U. Govender, Y. Tang, S. He, K. E. Hartman, C. A. O'Callaghan, G. S. Ogg, M. A. Altfeld, E. S. Rosenberg, H. Cao, S. A. Kalams, M. Hammond, M. Bunce, S. I. Pelton, S. A. Burchett, K. McIntosh, H. M. Coovadia, and B. D. Walker. Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children. J. Virol., 74:5679-90, 2000. PubMed ID: 10823876. Show all entries for this paper.


Displaying record number 58944

HXB2 Location Gag(269-277)
p24(137-145)
DNA(1594..1620)
Gag Epitope Map
Author Location Gag
Epitope GLNKIVRMY Epitope Alignment
GLNKIVRMY epitope logo
Subtype A
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya, Pakistan
Experimental methods Other
Keywords epitope processing

Notes

References

Abidi2013 Syed H. Abidi, Aniqa Shahid, Laila S. Lakhani, Muhammad R. Khanani, Peter Ojwang, Nancy Okinda, Reena Shah, Farhat Abbas, Sarah Rowland-Jones, and Syed Ali. Population-Specific Evolution of HIV Gag Epitopes in Genetically Diverged Patients. Infect. Genet. Evol., 16:78-86, Jun 2013. PubMed ID: 23403357. Show all entries for this paper.


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