HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 53092

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HXB2 Location Gag(193-203)
p24(61-71)
DNA(1366..1398)
Gag Epitope Map
Author Location p24(61-70)
Epitope GHQAAMQMLKE Epitope Alignment
GHQAAMQMLKE epitope logo
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Proliferation
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Plana2004 Montserrat Plana, Felipe Garcia, Annette Oxenius, Gabriel M. Ortiz, Anna Lopez, Anna Cruceta, Gabriel Mestre, Emilio Fumero, Catherine Fagard, Maria Antonia Sambeat, Ferran Segura, José M. Miró, Mireia Arnedo, L. Lopalcos, Tomas Pumarola, Bernard Hirschel, Rodney E. Phillips, Douglas F. Nixon, Teresa Gallart, and Jose M. Gatell. Relevance of HIV-1-Specific CD4+ Helper T-Cell Responses During Structured Treatment Interruptions in Patients With CD4+ T-Cell Nadir Above 400/mm3. J. Acquir. Immune Defic. Syndr., 36(3):791-799, 1 Jul 2004. PubMed ID: 15213562. Show all entries for this paper.


Displaying record number 55264

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HXB2 Location Gag(193-203)
p24(61-71)
DNA(1366..1398)
Gag Epitope Map
Author Location p24(61-77)
Epitope GHQAAMQMLKE Epitope Alignment
GHQAAMQMLKE epitope logo
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 57401

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HXB2 Location Gag(193-203)
p24(61-71)
DNA(1366..1398)
Gag Epitope Map
Author Location Gag(193-203)
Epitope GHQAAMQMLKE Epitope Alignment
GHQAAMQMLKE epitope logo
Epitope Name GE11
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen in vitro stimulation or selection, HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development, chronic infection

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 57712

Download this epitope record as JSON.

HXB2 Location Gag(193-203)
p24(61-71)
DNA(1366..1398)
Gag Epitope Map
Author Location Gag
Epitope GHQAAMQMLKE Epitope Alignment
GHQAAMQMLKE epitope logo
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supervised treatment interruptions (STI), escape

Notes

References

Schweighardt2010 Becky Schweighardt, Terri Wrin, Duncan A. Meiklejohn, Gerald Spotts, Christos J. Petropoulos, Douglas F. Nixon, and Frederick M. Hecht. Immune Escape Mutations Detected within HIV-1 Epitopes Associated with Viral Control During Treatment Interruption. J. Acquir. Immune Defic. Syndr., 53(1):36-46, Jan 2010. PubMed ID: 19910798. Show all entries for this paper.


Displaying record number 202

Download this epitope record as JSON.

HXB2 Location Gag(193-203)
p24(61-71)
DNA(1366..1398)
Gag Epitope Map
Author Location p24(193-203 BRU)
Epitope GHQAAMQMLKE Epitope Alignment
GHQAAMQMLKE epitope logo
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Claverie1988 J-M. Claverie, P. Kourilsky, P. Langlade-Demoyen, A. Chalufour-Prochnicka, G. Dadaglio, F. Tekaia, F. Plata, and K. Bougueleret. T-Immunogenic Peptides Are Constituted of Rare Sequence Patterns. Use in the Identification of T Epitopes in the Human Immunodeficiency Virus Gag Protein. Eur. J. Immunol., 18:1547-1553, 1988. Based on what was known about epitope structure and amino acid frequencies in 1988, the authors predicted epitopes in the gag proteins. Four peptides that were predicted to contain epitopes were found to specifically stimulate an HLA-A2 restricted polyclonal CTL cell line, when presented by mouse P815 target cells that had been transfected with HLA-A2. PubMed ID: 2461306. Show all entries for this paper.


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