HIV molecular immunology database
Found 8 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17 | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Epitope Name | GI9 | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression |
Streeck2014 Hendrik Streeck, Richard Lu, Noor Beckwith, Mark Milazzo, Michelle Liu, Jean-Pierre Routy, Susan Little, Heiko Jessen, Anthony D. Kelleher, Frederick Hecht, Rafick-Pierre Sekaly, Galit Alter, David Heckerman, Mary Carrington, Eric S. Rosenberg, and Marcus Altfeld. Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome. J. Virol., 88(21):12793-12801, Nov 2014. PubMed ID: 25165102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Epitope Name | GI9 | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | GI9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*40) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*30, B*18, B*40, C*02, C*05 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | responses in children, mother-to-infant transmission, escape, acute/early infection, viral fitness and reversion |
Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p15 | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Epitope Name | B40-GI9(p15) | |
Species (MHC/HLA) | human(B40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Epitope Name | Gag-GI9, p17-GI9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*40:02) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 01RCH46: A*02:01, A*02:17, B*08:01, B*40:02, C*03:03, C*07:01 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | HAART, ART, novel epitope |
Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*40:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*49:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 53617: A*02:01, A*02:05, B*27:05, B*49:01, C*02:02, C*07:01 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | acute/early infection |
Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(11-19) p17(11-19) DNA(820..846) |
Gag Epitope Map |
---|---|---|
Author Location | p17(11-19) | |
Epitope |
GELDRWEKI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.