HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 59298

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Epitope Name GI9
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression

Notes

References

Streeck2014 Hendrik Streeck, Richard Lu, Noor Beckwith, Mark Milazzo, Michelle Liu, Jean-Pierre Routy, Susan Little, Heiko Jessen, Anthony D. Kelleher, Frederick Hecht, Rafick-Pierre Sekaly, Galit Alter, David Heckerman, Mary Carrington, Eric S. Rosenberg, and Marcus Altfeld. Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome. J. Virol., 88(21):12793-12801, Nov 2014. PubMed ID: 25165102. Show all entries for this paper.


Displaying record number 59709

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location Gag(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Epitope Name GI9
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53844

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Show epitope variants
Epitope Name GI9
Subtype B
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Patient MHC/HLA A*30, B*18, B*40, C*02, C*05
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords responses in children, mother-to-infant transmission, escape, acute/early infection, viral fitness and reversion

Notes

References

Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.


Displaying record number 54366

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p15
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Epitope Name B40-GI9(p15)
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 1958

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Epitope Name Gag-GI9, p17-GI9
Subtype B
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Patient MHC/HLA 01RCH46: A*02:01, A*02:17, B*08:01, B*40:02, C*03:03, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords HAART, ART, novel epitope

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 52568

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HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 60944

Download this epitope record as JSON.

HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Subtype B
Species (MHC/HLA) human(B*49:01)
Immunogen HIV-1 infection
Patient MHC/HLA 53617: A*02:01, A*02:05, B*27:05, B*49:01, C*02:02, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 62626

Download this epitope record as JSON.

HXB2 Location Gag(11-19)
p17(11-19)
DNA(820..846)
Gag Epitope Map
Author Location p17(11-19)
Epitope GELDRWEKI Epitope Alignment
GELDRWEKI epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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