HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 54075

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location ( C consensus)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Subtype C
Species (MHC/HLA) human(A*0205)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 54084

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(A*0205)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 54604

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Subtype C
Species (MHC/HLA) human(A*0205)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Degranulation, CD107a and b cell surface mobilization, Intracellular cytokine staining, Proliferation, Tetramer binding
Keywords rate of progression

Notes

References

Day2007 Cheryl L. Day, Photini Kiepiela, Alasdair J. Leslie, Mary van der Stok, Kriebashne Nair, Nasreen Ismail, Isobella Honeyborne, Hayley Crawford, Hoosen M. Coovadia, Philip J. R. Goulder, Bruce D. Walker, and Paul Klenerman. Proliferative Capacity of Epitope-Specific CD8 T-cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 81(1):434-438, Jan 2007. PubMed ID: 17050606. Show all entries for this paper.


Displaying record number 55168

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(A*0205)
Immunogen HIV-1 infection
Country South Africa
Experimental methods Intracellular cytokine staining, Proliferation, Tetramer binding
Keywords  

Notes

References

Day2006 Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela, Julia A. Brown, Eshia S. Moodley, Sharon Reddy, Elizabeth W. Mackey, Joseph D. Miller, Alasdair J. Leslie, Chantal DePierres, Zenele Mncube, Jaikumar Duraiswamy, Baogong Zhu, Quentin Eichbaum, Marcus Altfeld, E. John Wherry, Hoosen M. Coovadia, Philip J. R. Goulder, Paul Klenerman, Rafi Ahmed, Gordon J. Freeman, and Bruce D. Walker. PD-1 Expression on HIV-Specific T Cells Is Associated with T-Cell Exhaustion and Disease Progression. Nature, 443(7109):350-354, 21 Sep 2006. PubMed ID: 16921384. Show all entries for this paper.


Displaying record number 61525

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Show epitope variants
Epitope Name Nef GL9-3F-7F
Subtype CRF01_AE
Species (MHC/HLA) human(A*0206)
Immunogen HIV-1 infection
Patient MHC/HLA KI-648: A*0206
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 56398

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Country Australia, Canada, Germany, United States
Experimental methods  
Keywords HLA associated polymorphism

Notes

References

Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.


Displaying record number 59708

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(B*1517)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59707

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(B*4202)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59706

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(C*03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59705

HXB2 Location Nef(83-91)
DNA(9043..9069)
Nef Epitope Map
Author Location Nef(83-91)
Epitope GAFDLSFFL Epitope Alignment
GAFDLSFFL epitope logo
Epitope Name GL9
Species (MHC/HLA) human(C*08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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