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HIV Molecular Immunology Database

Search CTL/CD8+ T-Cell Epitope Database

Found 11 matching records:

Displaying record number 59704

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location Pol(591-600)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55966

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location RT
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10(RT)
Subtype B
Species (MHC/HLA) human(A68)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 54119

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location RT(436-445)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Species (MHC/HLA) human(A*68:02)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 59700

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location Pol(591-600)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56251

Download this epitope record as JSON.

HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location  
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Subtype C
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Patient MHC/HLA A*23:01, A*68:02, B*15:10, B*58:02, C*05:11, C*06:11
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords rate of progression

Notes

References

Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.


Displaying record number 54018

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location ( C consensus)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Subtype C
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 59702

Download this epitope record as JSON.

HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location Pol(591-600)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10
Species (MHC/HLA) human(A*69)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59701

Download this epitope record as JSON.

HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location Pol(591-600)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10
Species (MHC/HLA) human(B*45)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 561

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HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location RT(591-600 IIIB)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Show epitope variants
Species (MHC/HLA) human(B45)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 59703

Download this epitope record as JSON.

HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location Pol(591-600)
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name GA10
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 63825

Download this epitope record as JSON.

HXB2 Location Pol(591-600)
RT(436-445)
DNA(3855..3884)
Pol Epitope Map
Author Location RT
Epitope GAETFYVDGA Epitope Alignment
GAETFYVDGA epitope logo
Epitope Name A68-GA10
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords immunodominance, acute/early infection, chronic infection

Notes

References

Streeck2009a Hendrik Streeck, Jonathan S. Jolin, Ying Qi, Bader Yassine-Diab, Randall C. Johnson, Douglas S. Kwon, Marylyn M. Addo, Chanson Brumme, Jean-Pierre Routy, Susan Little, Heiko K. Jessen, Anthony D. Kelleher, Frederick M. Hecht, Rafick-Pierre Sekaly, Eric S. Rosenberg, Bruce D. Walker, Mary Carrington, and Marcus Altfeld. Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells. J. Virol., 83(15):7641-7648, Aug 2009. PubMed ID: 19458000. Show all entries for this paper.


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