HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 52754

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location Gag(164-172)
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Patient MHC/HLA A28, A3, B53, B57
Experimental methods Chromium-release assay
Keywords TCR usage, genital and mucosal immunity

Notes

References

Musey2003 L. Musey, Y. Ding, J. Cao, J. Lee, C. Galloway, A. Yuen, K. R. Jerome, and M. J. McElrath. Ontogeny and Specificities of Mucosal and Blood Human Immunodeficiency Virus Type 1-Specific CD8+ Cytotoxic T Lymphocytes. J. Virol., 77(1):291-300, Jan 2003. PubMed ID: 12477834. Show all entries for this paper.


Displaying record number 53665

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location p24
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Epitope Name FF9
Subtype B, C
Species (MHC/HLA) human(B57, B58, B63)
Immunogen HIV-1 infection
Patient MHC/HLA A*74, A*8001, B*18, B*57, Cw*02, Cw*07
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HLA cross-presentation, optimal epitope

Notes

References

Frahm2005a Nicole Frahm, Sharon Adams, Photini Kiepiela, Caitlyn H. Linde, Hannah S. Hewitt, Mathias Lichterfeld, Kaori Sango, Nancy V. Brown, Eunice Pae, Alysse G. Wurcel, Marcus Altfeld, Margaret E. Feeney, Todd M. Allen, Timothy Roach, M. Anne St. John, Eric S. Daar, Eric Rosenberg, Bette Korber, Francesco Marincola, Bruce D. Walker, Philip J. R. Goulder, and Christian Brander. HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load. J. Virol., 79(16):10218-10225, Aug 2005. PubMed ID: 16051815. Show all entries for this paper.


Displaying record number 59698

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location Gag(164-172)
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Epitope Name FF9
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54129

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location  
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Species (MHC/HLA) human(B*57)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 60641

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location p24(32-40)
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Epitope Name FF-9
Subtype B, C
Species (MHC/HLA) human(B*57, B*58, B*63)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 59699

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location Gag(164-172)
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Epitope Name FF9
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57652

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location  
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Show epitope variants
Species (MHC/HLA) macaque(Mamu-A*01)
Immunogen vaccine
Experimental methods CD8 T-cell RecycleSpot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA, modified vaccinia Ankara (MVA), Semliki-Forest Virus, adenovirus, Long Peptides, HIVconsv
Adjuvant Montanide (ISA 51)

Notes

References

Rosario2010 Maximillian Rosario, Anne Bridgeman, Esther D. Quakkelaar, Maire F. Quigley, Brenna J. Hill, Maria L. Knudsen, Virginia Ammendola, Karl Ljungberg, Nicola Borthwick, Eung-Jun Im, Andrew J. McMichael, Jan W. Drijfhout, Hui Yee Greenaway, Vanessa Venturi, Daniel C. Douek, Stefano Colloca, Peter Liljeström, Alfredo Nicosia, David A. Price, Cornelis J. M. Melief, and Tomáš Hanke. Long Peptides Induce Polyfunctional T Cells against Conserved Regions of HIV-1 with Superior Breadth to Single-Gene Vaccines in Macaques. Eur. J. Immunol., 40(7):1973-1984, Jul 2010. PubMed ID: 20468055. Show all entries for this paper.


Displaying record number 58445

HXB2 Location Gag(164-172)
p24(32-40)
DNA(1279..1305)
Gag Epitope Map
Author Location p24(32-40)
Epitope FSPEVIPMF Epitope Alignment
FSPEVIPMF epitope logo
Subtype A1
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Proliferation
Keywords assay or method development, characterizing CD8+ T cells

Notes

References

Richmond2011 Meika Richmond, Lyle R. McKinnon, Sandra A. Koesters Kiazyk, Charles Wachihi, Makobu Kimani, Joshua Kimani, Francis A. Plummer, and T. Blake Ball. Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function. J. Virol., 85(3):1275-1286, Feb 2011. PubMed ID: 21084478. Show all entries for this paper.


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