HIV molecular immunology database
Found 15 matching records:
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(A*26) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | B15-FY10(Tat) | |
Species (MHC/HLA) | human(B15) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(B*15:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | subtype comparisons, rate of progression, immunodominance |
Frahm2006 Nicole Frahm, Photini Kiepiela, Sharon Adams, Caitlyn H. Linde, Hannah S. Hewitt, Kaori Sango, Margaret E. Feeney, Marylyn M. Addo, Mathias Lichterfeld, Matthew P. Lahaie, Eunice Pae, Alysse G. Wurcel, Timothy Roach, M Anne. St. John, Marcus Altfeld, Francesco M. Marincola, Corey Moore, Simon Mallal, Mary Carrington, David Heckerman, Todd M. Allen, James I. Mullins, Bette T. Korber, Philip J. R. Goulder, Bruce D. Walker, and Christian Brander. Control of Human Immunodeficiency Virus Replication by Cytotoxic T Lymphocytes Targeting Subdominant Epitopes. Nat. Immunol., 7(2):173-178, Feb 2006. PubMed ID: 16369537. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | ||
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa, United Kingdom | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Tetramer binding | |
Keywords | computational epitope prediction, optimal epitope |
ErupLarsen2011 Malene Erup Larsen, Henrik Kloverpris, Anette Stryhn, Catherine K. Koofhethile, Stuart Sims, Thumbi Ndung'u, Philip Goulder, Søren Buus, and Morten Nielsen. HLArestrictor---A Tool for Patient-Specific Predictions of HLA Restriction Elements and Optimal Epitopes within Peptides. Immunogenetics, 63(1):43-55, Jan 2011. PubMed ID: 21079948. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(67-76) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10-Tat | |
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Tetramer binding | |
Keywords | TCR usage, characterizing CD8+ T cells |
Kloverpris2014a Henrik N. Kløverpris, Reuben McGregor, James E McLaren, Kristin Ladell, Anette Stryhn, Catherine Koofhethile, Jacqui Brener, Fabian Chen, Lynn Riddell, Luzzi Graziano, Paul Klenerman, Alasdair Leslie, Søren Buus, David A. Price, and Philip Goulder. Programmed Death-1 Expression on HIV-1-Specific CD8+ T Cells Is Shaped by Epitope Specificity, T-Cell Receptor Clonotype Usage and Antigen Load. AIDS, 28(14):2007-2021, 10 Sep 2014. PubMed ID: 24906112. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | ( subtype C) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | T38-FY10 | |
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Country | Botswana | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | immunodominance, optimal epitope |
Novitsky2001 V. Novitsky, N. Rybak, M. F. McLane, P. Gilbert, P. Chigwedere, I. Klein, S. Gaolekwe, S. Y. Chang, T. Peter, I. Thior, T. Ndung'u, F. Vannberg, B. T. Foley, R. Marlink, T. H. Lee, and M. Essex. Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design. J. Virol., 75(19):9210-28, Oct 2001. URL: http://jvi.asm.org/cgi/content/full/75/19/9210. PubMed ID: 11533184. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | characterizing CD8+ T cells |
Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, optimal epitope |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(B*15:03) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(B*15:40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(C*06) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Tat(38-47) DNA(5942..5971) |
Tat Epitope Map |
---|---|---|
Author Location | Tat(38-47) | |
Epitope |
FQTKGLGISY
|
Epitope Alignment
|
Epitope Name | FY10 | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.