HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 61172

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HXB2 Location Nef(68-77)
DNA(8998..9027)
Nef Epitope Map
Author Location Nef(68-77)
Epitope FPVRPQVPLR Epitope Alignment
FPVRPQVPLR epitope logo
Show epitope variants
Epitope Name FR10
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 1419

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HXB2 Location Nef(68-77)
DNA(8998..9027)
Nef Epitope Map
Author Location Nef(66-75)
Epitope FPVRPQVPLR Epitope Alignment
FPVRPQVPLR epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 54547

Download this epitope record as JSON.

HXB2 Location Nef(68-77)
DNA(8998..9027)
Nef Epitope Map
Author Location Nef(68-77)
Epitope FPVRPQVPLR Epitope Alignment
FPVRPQVPLR epitope logo
Epitope Name FR10
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection, assay or method development, mutation acquisition

Notes

References

Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.


Displaying record number 55973

Download this epitope record as JSON.

HXB2 Location Nef(68-77)
DNA(8998..9027)
Nef Epitope Map
Author Location Nef
Epitope FPVRPQVPLR Epitope Alignment
FPVRPQVPLR epitope logo
Show epitope variants
Epitope Name FR10(Nef)
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 62738

Download this epitope record as JSON.

HXB2 Location Nef(68-77)
DNA(8998..9027)
Nef Epitope Map
Author Location Nef(68-77)
Epitope FPVRPQVPLR Epitope Alignment
FPVRPQVPLR epitope logo
Show epitope variants
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods Other
Keywords subtype comparisons, class I down-regulation by Nef, HLA associated polymorphism, Nef-mediated down-regulation

Notes

References

Naidoo2019 Lisa Naidoo, Zinhle Mzobe, Steven W. Jin, Erasha Rajkoomar, Tarylee Reddy, Mark A. Brockman, Zabrina L. Brumme, Thumbi Ndung'u, and Jaclyn K. Mann. Nef-Mediated Inhibition of NFAT Following TCR Stimulation Differs Between HIV-1 Subtypes. Virology, 531:192-202, May 2019. PubMed ID: 30927712. Show all entries for this paper.


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