HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 61034

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HXB2 Location Nef(68-76)
DNA(8998..9024)
Nef Epitope Map
Author Location Nef
Epitope FPVKPQVPL Epitope Alignment
FPVKPQVPL epitope logo
Epitope Name FKL9
Subtype C
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Other
Keywords escape, mutation acquisition

Notes

References

Carlson2016 Jonathan M. Carlson, Victor Y. Du, Nico Pfeifer, Anju Bansal, Vincent Y. F. Tan, Karen Power, Chanson J. Brumme, Anat Kreimer, Charles E. DeZiel, Nicolo Fusi, Malinda Schaefer, Mark A. Brockman, Jill Gilmour, Matt A. Price, William Kilembe, Richard Haubrich, Mina John, Simon Mallal, Roger Shapiro, John Frater, P. Richard Harrigan, Thumbi Ndung'u, Susan Allen, David Heckerman, John Sidney, Todd M. Allen, Philip J. R. Goulder, Zabrina L. Brumme, Eric Hunter, and Paul A. Goepfert. Impact of Pre-Adapted HIV Transmission. Nat. Med., 22(6):606-613, Jun 2016. PubMed ID: 27183217. Show all entries for this paper.


Displaying record number 61175

Download this epitope record as JSON.

HXB2 Location Nef(68-76)
DNA(8998..9024)
Nef Epitope Map
Author Location Nef(68-76)
Epitope FPVKPQVPL Epitope Alignment
FPVKPQVPL epitope logo
Show epitope variants
Epitope Name FKL9
Subtype B
Species (MHC/HLA) human(B*07:02)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 54548

Download this epitope record as JSON.

HXB2 Location Nef(68-76)
DNA(8998..9024)
Nef Epitope Map
Author Location Nef(68-76)
Epitope FPVKPQVPL Epitope Alignment
FPVKPQVPL epitope logo
Epitope Name FL9
Subtype B
Species (MHC/HLA) human(B35, B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection, assay or method development, mutation acquisition

Notes

References

Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.


Displaying record number 60943

Download this epitope record as JSON.

HXB2 Location Nef(68-76)
DNA(8998..9024)
Nef Epitope Map
Author Location Nef(68-76)
Epitope FPVKPQVPL Epitope Alignment
FPVKPQVPL epitope logo
Subtype B
Species (MHC/HLA) human(B35, B7)
Immunogen HIV-1 infection
Patient MHC/HLA 71101: A*01:01, A*03:01, B*08:01, B*35:03, C*04:01, C*07:01; 63794: A*02:01:01G, B*07:02:01G, B*44:02:01G, C*07:04:01G
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


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