HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 781

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HXB2 Location gp160(376-383)
gp120(376-383)
DNA(7350..7373)
gp160 Epitope Map
Author Location gp120(376-383)
Epitope FNCGGEFF Epitope Alignment
FNCGGEFF epitope logo
Species (MHC/HLA) human(Cw4)
Immunogen HIV-1 infection
Country Gambia
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS), variant cross-reactivity, HIV-2

Notes

References

Johnson1993 R. P. Johnson, A. Trocha, T. M. Buchanan, and B. D. Walker. Recognition of a Highly Conserved Region of Human Immunodeficiency Virus Type 1 gp120 by an HLA-Cw4-Restricted Cytotoxic T-Lymphocyte Clone. J. Virol., 67:438-445, 1993. The epitope sequence FNCGGEFF stimulates CTL response; the natural variants FNCRGEFF (SF2), TNCRGEFL (ROD) and LNCGGEFF (NDK) do not serve as epitopes. This was the first report of an HIV antigen specific target cells restricted by an HLA-C molecule, Cw4. PubMed ID: 7677956. Show all entries for this paper.

Rowland-Jones1999 S. L. Rowland-Jones, T. Dong, L. Dorrell, G. Ogg, P. Hansasuta, P. Krausa, J. Kimani, S. Sabally, K. Ariyoshi, J. Oyugi, K. S. MacDonald, J. Bwayo, H. Whittle, F. A. Plummer, and A. J. McMichael. Broadly Cross-Reactive HIV-Specific Cytotoxic T Lymphocytes in Highly-Exposed Persistently Seronegative Donors. Immunol. Lett., 66:9-14, 1999. PubMed ID: 10203028. Show all entries for this paper.


Displaying record number 55138

Download this epitope record as JSON.

HXB2 Location gp160(376-383)
gp120(376-383)
DNA(7350..7373)
gp160 Epitope Map
Author Location gp120(376-383)
Epitope FNCGGEFF Epitope Alignment
FNCGGEFF epitope logo
Show epitope variants
Species (MHC/HLA) human(Cw4)
Immunogen  
Experimental methods  
Keywords subtype comparisons, viral fitness and reversion

Notes

References

Queiroz2007 Artur Trancoso Lopo de Queiroz, Luciane Amorim Santos, Domingos Ramon Moreau, Tulio de Oliveira, David I. Watkins, Bernardo Galvão-Castro, and Luiz Carlos Junior Alcantara. Identification and Characterization of Previously Described Epitopes in HIV-1 Subtypes B, C, F and BF in Brazil. Braz. J. Infect. Dis., 11(1):27-30, Feb 2007. PubMed ID: 17625722. Show all entries for this paper.


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