HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 54579

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HXB2 Location Gag(93-101)
p17(93-101)
DNA(1066..1092)
Gag Epitope Map
Author Location Gag(93-101)
Epitope EVKDTKEAL Epitope Alignment
EVKDTKEAL epitope logo
Show epitope variants
Epitope Name EL9
Subtype B
Species (MHC/HLA) human(B*08)
Immunogen HIV-1 infection
Patient MHC/HLA A*01, A*02
Country United States
Experimental methods Intracellular cytokine staining, Other
Keywords rate of progression, escape, mutation acquisition

Notes

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


Displaying record number 53230

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HXB2 Location Gag(93-101)
p17(93-101)
DNA(1066..1092)
Gag Epitope Map
Author Location Gag(99-107 WEAU)
Epitope EVKDTKEAL Epitope Alignment
EVKDTKEAL epitope logo
Epitope Name Gag EVL9
Subtype B
Species (MHC/HLA) human(B*08:01)
Immunogen HIV-1 infection
Patient MHC/HLA WEAU: A01, A29, B08, B44
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords dynamics, acute/early infection, kinetics, autologous responses, optimal epitope

Notes

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.

Yang2019 Yiding Yang, and Vitaly V. Ganusov. Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection. Microorganisms, 7(3):microorganisms7030069 doi, Mar 2019. PubMed ID: 30836625 Show all entries for this paper.


Displaying record number 53822

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HXB2 Location Gag(93-101)
p17(93-101)
DNA(1066..1092)
Gag Epitope Map
Author Location p17
Epitope EVKDTKEAL Epitope Alignment
EVKDTKEAL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*08:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*01:01, A*03:01, B*08:01, B*51:01; A*01:01, B*08:01
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords escape, acute/early infection, variant cross-reactivity

Notes

References

Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.


Displaying record number 58197

Download this epitope record as JSON.

HXB2 Location Gag(93-101)
p17(93-101)
DNA(1066..1092)
Gag Epitope Map
Author Location Gag/Pol(94- CDC-451)
Epitope EVKDTKEAL Epitope Alignment
EVKDTKEAL epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen computer prediction
Experimental methods  
Keywords T-cell crossreactivity to human proteins

Notes

References

Lucchese2011 Guglielmo Lucchese, Angela Stufano, Michele Calabro, and Darja Kanduc. Charting the Peptide Crossreactome between HIV-1 and the Human Proteome. Front. Biosci. (Elite Ed.), 3E:1385-1400, 2011. PubMed ID: 21622144. Show all entries for this paper.


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