HIV molecular immunology database
Found 12 matching records:
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | Vpr-EV10 | |
Subtype | C | |
Species (MHC/HLA) | human(A*68) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 517-C: A*30:02, A*68:02, B*15:10, B*42:01, C*03:04, C*17:01; 517-M: A*30:02, A*30:04, B*42:01, B*58:02, C*06:02, C*17:01 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | dynamics, responses in children, mother-to-infant transmission, rate of progression, escape |
Leitman2017 Ellen M. Leitman, Christina F. Thobakgale, Emily Adland, M. Azim Ansari, Jayna Raghwani, Andrew J. Prendergast, Gareth Tudor-Williams, Photini Kiepiela, Joris Hemelaar, Jacqui Brener, Ming-Han Tsai, Masahiko Mori, Lynn Riddell, Graz Luzzi, Pieter Jooste, Thumbi Ndung'u, Bruce D. Walker, Oliver G. Pybus, Paul Kellam, Vivek Naranbhai, Philippa C. Matthews, Astrid Gall, and Philip J. R. Goulder. Role of HIV-Specific CD8+ T Cells in Pediatric HIV Cure Strategies after Widespread Early Viral Escape. J. Exp. Med., 214(11):3239-3261, 6 Nov 2017. PubMed ID: 28983013. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | Other | |
Keywords | HLA associated polymorphism |
Boutwell2007 Christian L. Boutwell and M. Essex. Identification of HLA Class I-Associated Amino Acid Polymorphisms in the HIV-1C Proteome. AIDS Res. Hum. Retroviruses, 23(1):165-174, Jan 2007. PubMed ID: 17263647. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | ||
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*68:02, B*15:10, C*03:04 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | rate of progression |
Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | Vpr-EV10 | |
Subtype | C | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Country | United Kingdom | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding | |
Keywords | optimal epitope, novel epitope |
Kloverpris2013c Henrik N. Kløverpris, Anette Stryhn, Mikkel Harndahl, Jonathan M. Carlson, Alasdair J. Leslie, Fabian Chen, Lynn Riddell, Joseph Mulenga, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-A*68:02-Restricted Gag-Specific Cytotoxic T Lymphocyte Responses Can Drive Selection Pressure on HIV but Are Subdominant and Ineffective. AIDS, 27(11):1717-1723, 17 Jul 2013. PubMed ID: 23525031. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, optimal epitope |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Epitope Name | EV10 | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Epitope Name | EV10 | |
Subtype | B | |
Species (MHC/HLA) | human(A*68:02) | |
Immunogen | HIV-1 infection | |
Country | Japan | |
Experimental methods | Other | |
Keywords | HLA associated polymorphism |
Kamori2017 Doreen Kamori, Zafrul Hasan, Jun Ohashi, Ai Kawana-Tachikawa, Hiroyuki Gatanaga, Shinichi Oka, and Takamasa Ueno. Identification of Two Unique Naturally Occurring Vpr Sequence Polymorphisms Associated with Clinical Parameters in HIV-1 Chronic Infection. J. Med. Virol., 89(1):123-129, Jan 2017. PubMed ID: 27328918. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Epitope Name | EV10 | |
Species (MHC/HLA) | human(A*69) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Epitope Name | EV10 | |
Species (MHC/HLA) | human(B*39) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Epitope Name | EV10 | |
Species (MHC/HLA) | human(C*14) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(48-57) DNA(5700..5729) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(48-57) | |
Epitope |
ETYGDTWTGV
|
Epitope Alignment
|
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | computational epitope prediction, HLA associated polymorphism |
Srinivasan2008 Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S. Kalyanaraman, Anthony Cristillo, Ronald G. Collman, Nelly Morellet, Bassel E. Sawaya, and Ramachandran Murali. A Comprehensive Analysis of the Naturally Occurring Polymorphisms in HIV-1 Vpr: Potential Impact on CTL Epitopes. Virol. J., 5:99, 2008. PubMed ID: 18721481. Show all entries for this paper.