HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 9 matching records:

Displaying record number 59619

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name EW10
Species (MHC/HLA) human(A*25)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59621

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name EW10
Species (MHC/HLA) human(B*15:24)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59620

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name EW10
Species (MHC/HLA) human(B*35:01, B*35:08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59622

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name EW10
Species (MHC/HLA) human(B*35:02, B*35:03, B*53:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55046

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location  
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Species (MHC/HLA) human(B53)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 52413

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Species (MHC/HLA) human(B53)
Immunogen HIV-1 infection
Experimental methods  
Keywords early-expressed proteins

Notes

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.


Displaying record number 52585

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name EW10
Species (MHC/HLA) human(B53)
Immunogen HIV-1 infection
Experimental methods Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords class I down-regulation by Nef

Notes

References

Bobbitt2003 Kevin R. Bobbitt, Marylyn M. Addo, Marcus Altfeld, Tracey Filzen, Adewunmi A. Onafuwa, Bruce D. Walker, and Kathleen L. Collins. Rev Activity Determines Sensitivity of HIV-1-Infected Primary T Cells to CTL killing. Immunity, 18(2):289-299, Feb 2003. PubMed ID: 12594955. Show all entries for this paper.


Displaying record number 1271

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat(2-11 BRU)
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name Tat 1
Species (MHC/HLA) human(B53)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Addo2001 Marylyn M. Addo, Marcus Altfeld, Eric S. Rosenberg, Robert L. Eldridge, Mary N. Philips, Kathleen Habeeb, Ashok Khatri, Christian Brander, Gregory K. Robbins, Gail P. Mazzara, Philip J. R. Goulder, and Bruce D. Walker. The HIV-1 Regulatory Proteins Tat and Rev are Freqently Targeted by cytotoxic T Lymphocytes (CTL) Derived from HIV Infected Individuals. Proc. Natl. Acad. Sci. U.S.A., 98(4):1781-1786, 13 Feb 2001. PubMed ID: 11172028. Show all entries for this paper.


Displaying record number 2007

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat
Epitope EPVDPRLEPW Epitope Alignment
EPVDPRLEPW epitope logo
Epitope Name Tat-EW10
Subtype B
Species (MHC/HLA) human(B*53:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


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