HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 53306

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HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location ( C consensus)
Epitope EPVDPNLEPW Epitope Alignment
EPVDPNLEPW epitope logo
Subtype C
Species (MHC/HLA) human(B*53:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 54048

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location ( C consensus)
Epitope EPVDPNLEPW Epitope Alignment
EPVDPNLEPW epitope logo
Subtype C
Species (MHC/HLA) human(B*53:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 56449

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat
Epitope EPVDPNLEPW Epitope Alignment
EPVDPNLEPW epitope logo
Epitope Name EW10(Tat)
Subtype B
Species (MHC/HLA) human(B58)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56111

Download this epitope record as JSON.

HXB2 Location Tat(2-11)
DNA(5834..5863)
Tat Epitope Map
Author Location Tat
Epitope EPVDPNLEPW Epitope Alignment
EPVDPNLEPW epitope logo
Epitope Name Tat1140
Subtype C
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, computational epitope prediction, HLA associated polymorphism

Notes

References

DeGroot2008 Anne S. De Groot, Daniel S. Rivera, Julie A. McMurry, Soren Buus, and William Martin. Identification of Immunogenic HLA-B7 ``Achilles' Heel'' Epitopes within Highly Conserved Regions of HIV. Vaccine, 26(24):3059-3071, 6 Jun 2008. PubMed ID: 18206276. Show all entries for this paper.


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