HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 57335

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol(587-)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Epitope Name Pol587
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country Japan
Experimental methods Chromium-release assay, Cytotoxicity assay, Intracellular cytokine staining, Proliferation, Tetramer binding
Keywords binding affinity

Notes

References

Ueno2007 Takamasa Ueno, Yuka Idegami, Chihiro Motozono, Shinichi Oka, and Masafumi Takiguchi. Altering Effects of Antigenic Variations in HIV-1 on Antiviral Effectiveness of HIV-Specific CTLs. J. Immunol., 178(9):5513-5523, 1 May 2007. PubMed ID: 17442933. Show all entries for this paper.


Displaying record number 53042

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Koning2004 Fransje A. Koning, Christine A. Jansen, Jos Dekker, Richard A. Kaslow, Nicole Dukers, Debbie van Baarle, Maria Prins, and Hanneke Schuitemaker. Correlates of Resistance to HIV-1 Infection in Homosexual Men with High-Risk Sexual Behaviour. AIDS, 18(8):1117-1126, 21 May 2004. PubMed ID: 15166527. Show all entries for this paper.


Displaying record number 557

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol(587-595)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Dyer1999 W. B. Dyer, G. S. Ogg, M. A. Demoitie, X. Jin, A. F. Geczy, S. L. Rowland-Jones, A. J. McMichael, D. F. Nixon, and J. S. Sullivan. Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected with nef-Defective HIV Type 1. J. Virol., 73:436-443, 1999. PubMed ID: 9847349. Show all entries for this paper.


Displaying record number 555

Download this epitope record as JSON.

HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location  
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords acute/early infection

Notes

References

Wilson2000 J. D. Wilson, G. S. Ogg, R. L. Allen, C. Davis, S. Shaunak, J. Downie, W. Dyer, C. Workman, S. Sullivan, A. J. McMichael, and S. L. Rowland-Jones. Direct Visualization of HIV-1-Specific Cytotoxic T Lymphocytes During Primary Infection. AIDS, 14:225-233, 2000. PubMed ID: 10716497. Show all entries for this paper.


Displaying record number 556

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location RT(587-596 SF2)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B35, B51)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Shiga1996 H. Shiga, T. Shioda, H. Tomiyama, Y. Takamiya, S. Oka, S. Kimura, Y. Yamaguchi, T. Gojoubori, H. G. Rammensee, K. Miwa, and M. Takiguchi. Identification of Multiple HIV-1 Cytotoxic T Cell Epitopes Presented by Human Leukocyte Antigen B35 Molecule. AIDS, 10:1075-1083, 1996. PubMed ID: 8874623. Show all entries for this paper.


Displaying record number 1425

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol(587-595)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B35, B51)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 554

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HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location RT(587-597 SF2)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Show epitope variants
Species (MHC/HLA) human(B*35:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords review

Notes

References

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.

Tomiyama1997 H. Tomiyama, K. Miwa, H. Shiga, Y. I. Moore, S. Oka, A. Iwamoto, Y. Kaneko, and M. Takiguchi. Evidence of Presentation of Multiple HIV-1 Cytotoxic T Lymphocyte Epitopes by HLA-B*3501 Molecules That Are Associated with the Accelerated Progression of AIDS. J. Immunol., 158:5026-5034, 1997. PubMed ID: 9144523. Show all entries for this paper.


Displaying record number 1340

Download this epitope record as JSON.

HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol(587-595)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B*35:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tomiyama2000a H. Tomiyama, S. Oka, G. S. Ogg, S. Ida, A. J. McMichael, and M. Takiguchi. Expansion of HIV-1-specific CD28- CD45RA- CD8+ T cells in chronically HIV-1-infected individuals. AIDS, 14(13):2049-51, 8 Sep 2000. PubMed ID: 10997412. Show all entries for this paper.


Displaying record number 52983

Download this epitope record as JSON.

HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location RT(432-440)
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, C*03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 58082

Download this epitope record as JSON.

HXB2 Location Pol(587-595)
RT(432-440)
DNA(3843..3869)
Pol Epitope Map
Author Location Pol
Epitope EPIVGAETF Epitope Alignment
EPIVGAETF epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A*33:01, A*74:01, B*53:01, B*78:01, C*04:01, C*16:01
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


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