HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 54153

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HXB2 Location Pol(359-367)
RT(204-212)
DNA(3159..3185)
Pol Epitope Map
Author Location RT(204-212 HXB2)
Epitope ELRQHLLRW Epitope Alignment
ELRQHLLRW epitope logo
Show epitope variants
Epitope Name EW9
Subtype B
Species (MHC/HLA) human(A*25:01)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, optimal epitope

Notes

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


Displaying record number 58162

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HXB2 Location Pol(359-367)
RT(204-212)
DNA(3159..3185)
Pol Epitope Map
Author Location RT(204-212)
Epitope ELRQHLLRW Epitope Alignment
ELRQHLLRW epitope logo
Epitope Name EW9
Subtype B
Species (MHC/HLA) human(A*25:01)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection

Notes

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


Displaying record number 59085

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HXB2 Location Pol(359-367)
RT(204-212)
DNA(3159..3185)
Pol Epitope Map
Author Location RT(204-212)
Epitope ELRQHLLRW Epitope Alignment
ELRQHLLRW epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*25:01)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion

Notes

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 58086

Download this epitope record as JSON.

HXB2 Location Pol(359-367)
RT(204-212)
DNA(3159..3185)
Pol Epitope Map
Author Location Pol
Epitope ELRQHLLRW Epitope Alignment
ELRQHLLRW epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A*01:01, A*11:01, B*15:01, B*44:03, C*03:04, C*16:01
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


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