HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 54033

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HXB2 Location Pol(872-881)
Integrase(157-166)
DNA(4698..4727)
Pol Epitope Map
Author Location ( C consensus)
Epitope ELKKIIGQVR Epitope Alignment
ELKKIIGQVR epitope logo
Subtype C
Species (MHC/HLA) human(A*33)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 58650

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HXB2 Location Pol(872-881)
Integrase(157-166)
DNA(4698..4727)
Pol Epitope Map
Author Location Integrase(157-166 NL4-3)
Epitope ELKKIIGQVR Epitope Alignment
ELKKIIGQVR epitope logo
Show epitope variants
Epitope Name ER10
Subtype B
Species (MHC/HLA) human(A*33)
Immunogen HIV-1 infection
Country Australia, Canada, Germany, United States
Experimental methods CD8 T-cell Elispot - IFNγ, Relative replication capacity assay
Keywords acute/early infection, HLA associated polymorphism

Notes

References

Brockman2012 Mark A. Brockman, Denis R. Chopera, Alex Olvera, Chanson J. Brumme, Jennifer Sela, Tristan J. Markle, Eric Martin, Jonathan M. Carlson, Anh Q. Le, Rachel McGovern, Peter K. Cheung, Anthony D. Kelleher, Heiko Jessen, Martin Markowitz, Eric Rosenberg, Nicole Frahm, Jorge Sanchez, Simon Mallal, Mina John, P. Richard Harrigan, David Heckerman, Christian Brander, Bruce D. Walker, and Zabrina L. Brumme. Uncommon Pathways of Immune Escape Attenuate HIV-1 Integrase Replication Capacity. J. Virol., 86(12):6913-6923, Jun 2012. PubMed ID: 22496233. Show all entries for this paper.


Displaying record number 55349

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HXB2 Location Pol(872-881)
Integrase(157-166)
DNA(4698..4727)
Pol Epitope Map
Author Location Integrase
Epitope ELKKIIGQVR Epitope Alignment
ELKKIIGQVR epitope logo
Epitope Name ER9
Species (MHC/HLA) human(A*33:01)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Zimbwa2007 Peter Zimbwa, Anita Milicic, John Frater, Thomas J. Scriba, Antony Willis, Philip J. R. Goulder, Tilly Pillay, Huldrych Gunthard, Jonathan N. Weber, Hua-Tang Zhang, and Rodney E. Phillips. Precise Identification of a Human Immunodeficiency Virus Type 1 Antigen Processing Mutant. J. Virol., 81(4):2031-2038, Feb 2007. PubMed ID: 17108020. Show all entries for this paper.


Displaying record number 61551

Download this epitope record as JSON.

HXB2 Location Pol(872-881)
Integrase(157-166)
DNA(4698..4727)
Pol Epitope Map
Author Location Integrase(157-166)
Epitope ELKKIIGQVR Epitope Alignment
ELKKIIGQVR epitope logo
Epitope Name Pol ER10
Subtype B, CRF01_AE
Species (MHC/HLA) human(A*33:03)
Immunogen HIV-1 infection
Patient MHC/HLA KI-632: A*24:02, A*33:03
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords optimal epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 61856

Download this epitope record as JSON.

HXB2 Location Pol(872-881)
Integrase(157-166)
DNA(4698..4727)
Pol Epitope Map
Author Location  
Epitope ELKKIIGQVR Epitope Alignment
ELKKIIGQVR epitope logo
Epitope Name ER10
Subtype B
Species (MHC/HLA) human(A*33:03)
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA KI-1427: A*33:03
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses

Notes

References

Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.


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