HIV molecular immunology database


Search CTL/CD8+ T-Cell Epitope Database

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Displaying record number 1022

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HXB2 Location Nef(93-106)
Nef Epitope Map
Author Location Nef(93-106 BRU)
Epitope EKGGLEGLIHSQRR Epitope Alignment
Species (MHC/HLA) human(A1, B8)
Immunogen HIV-1 infection
Experimental methods  



Hadida1992 F. Hadida, A. Parrot, M. P. Kieny, B. Sadat-Sowti, C. Mayaud, and P. Debre. Carboxyl-Terminal and Central Regions of Human Immunodeficiency Virus-1 NEF Recognized by Cytotoxic T Lymphocytes from Lymphoid Organs. An In Vitro Limiting Dilution Analysis. J. Clin. Invest., 89:53-60, 1992. HIV-1-specific CTL can be detected in lymph nodes and spleens. The carboxyl-terminal domain of Nef is recognized by CTL in association with HLA-A1 and B8, with clonal frequencies of one CTL per $10^-5$ to $10^-6$ splenic lymphocytes. PubMed ID: 1370302. Show all entries for this paper.

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