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Displaying record number 1022

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HXB2 Location	Nef(93-106) DNA(9073..9114)	Nef Epitope Map
Author Location	Nef(93-106 BRU)
Epitope	EKGGLEGLIHSQRR	Epitope Alignment
Species (MHC/HLA)	human(A1, B8)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

• HIV-1 specific CTLs detected in lymphoid organs of HIV-1 infected patients.

References

Hadida1992 F. Hadida, A. Parrot, M. P. Kieny, B. Sadat-Sowti, C. Mayaud, and P. Debre. Carboxyl-Terminal and Central Regions of Human Immunodeficiency Virus-1 NEF Recognized by Cytotoxic T Lymphocytes from Lymphoid Organs. An In Vitro Limiting Dilution Analysis. J. Clin. Invest., 89:53-60, 1992. HIV-1-specific CTL can be detected in lymph nodes and spleens. The carboxyl-terminal domain of Nef is recognized by CTL in association with HLA-A1 and B8, with clonal frequencies of one CTL per $10^-5$ to $10^-6$ splenic lymphocytes. PubMed ID: 1370302. Show all entries for this paper.