HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 14 matching records:

Displaying record number 59612

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location Pol(197-205)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59610

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location Pol(197-205)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59613

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location Pol(197-205)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*35:01, B*35:08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59611

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location Pol(197-205)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*35:02, B*35:03, B*53:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59609

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location Pol(197-205)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*49)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59376

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location  
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Species (MHC/HLA) human(B*49:01)
Immunogen HIV-1 infection
Patient MHC/HLA T06: A*01:01, A*30:04, B*08:01, B*49:01, C*07:01
Country Germany
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords computational epitope prediction, optimal epitope

Notes

References

Roider2014 Julia Roider, Tim Meissner, Franziska Kraut, Thomas Vollbrecht, Renate Stirner, Johannes R. Bogner, and Rika Draenert. Comparison of Experimental Fine-Mapping to In Silico Prediction Results of HIV-1 Epitopes Reveals Ongoing Need for Mapping Experiments. Immunology, 143(2):193-201, Oct 2014. PubMed ID: 24724694. Show all entries for this paper.


Displaying record number 416

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT(42-50 LAI)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Subtype B
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Haas1998 G. Haas, A. Samri, E. Gomard, A. Hosmalin, J. Duntze, J. M. Bouley, H. G. Ihlenfeldt, C. Katlama, and B. Autran. Cytotoxic T Cell Responses to HIV-1 Reverse Transcriptase, Integrase and Protease. AIDS, 12(12):1427-1436, 1998. PubMed ID: 9727563. Show all entries for this paper.


Displaying record number 52972

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT(42-50)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, C*03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 55044

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location  
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 56444

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9(RT)
Subtype B
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 59076

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT(42-50)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Subtype B
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion

Notes

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 54320

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT(42-50)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other
Keywords vaccine-induced immune responses, HLA cross-presentation, HLA associated polymorphism

Notes

References

Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.


Displaying record number 54150

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT(42-50 HXB2)
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Epitope Name EI9
Subtype B
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, optimal epitope

Notes

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


Displaying record number 61266

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HXB2 Location Pol(197-205)
RT(42-50)
DNA(2673..2699)
Pol Epitope Map
Author Location RT
Epitope EKEGKISKI Epitope Alignment
EKEGKISKI epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Mexico, Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords drug resistance

Notes

References

Blanco-Heredia2016 Juan Blanco-Heredia, Aarón Lecanda, Humberto Valenzuela-Ponce, Christian Brander, Santiago Ávila-Rios, and Gustavo Reyes-Terán. Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naive HIV-Infected Individuals. PLoS One, 11(1):e0147571, 2016. PubMed ID: 26808823. Show all entries for this paper.


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