HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 22 matching records:

Displaying record number 59591

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(A*33)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59592

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(A*6802)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59587

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59593

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59590

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*3501, B*3508)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59586

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*3502, B*3503, B*5301)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55832

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Subtype B
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords binding affinity

Notes

References

Cao2008 Jianhong Cao, John McNevin, Matthew McSweyn, Yi Liu, James I. Mullins, and M. Juliana McElrath. Novel Cytotoxic T-Lymphocyte Escape Mutation by a Three-Amino-Acid Insertion in the Human Immunodeficiency Virus Type 1 p6Pol and p6Gag Late Domain Associated with Drug Resistance. J. Virol., 82(1):495-502, Jan 2008. PubMed ID: 17942528. Show all entries for this paper.


Displaying record number 59588

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57587

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Subtype B
Species (MHC/HLA) (B*51)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Dinges2010 Warren L. Dinges, Julia Richardt, David Friedrich, Emilie Jalbert, Yi Liu, Claire E. Stevens, Janine Maenza, Ann C. Collier, Daniel E. Geraghty, Jeremy Smith, Zoe Moodie, James I. Mullins, M. Juliana McElrath, and Helen Horton. Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype. J. Virol., 84(9):4461-4468, May 2010. PubMed ID: 20147397. Show all entries for this paper.


Displaying record number 58012

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Show epitope variants
Epitope Name EI9
Subtype B
Species (MHC/HLA) human(B*51)
Immunogen in vitro stimulation or selection
Experimental methods Chromium-release assay, Cytotoxicity assay, Other
Keywords epitope processing, escape

Notes

References

Lazaro2011 Estibaliz Lazaro, Carl Kadie, Pamela Stamegna, Shao Chong Zhang, Pauline Gourdain, Nicole Y. Lai, Mei Zhang, Sergio A. Martinez, David Heckerman, and Sylvie Le Gall. Variable HIV Peptide Stability in Human Cytosol Is Critical to Epitope Presentation and Immune Escape. J. Clin. Invest., 121(6):2480-2492, Jun 2011. PubMed ID: 21555856. Show all entries for this paper.


Displaying record number 58400

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location ( IIIB, MN)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Subtype B
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication
Keywords rate of progression, HLA associated polymorphism, elite controllers

Notes

References

Zhang2011 YongHong Zhang, YanChun Peng, HuiPing Yan, Keyi Xu, Masumichi Saito, Hao Wu, XinYue Chen, Srinika Ranasinghe, Nozomi Kuse, Tim Powell, Yan Zhao, WeiHua Li, Xin Zhang, Xia Feng, Ning Li, Aleksandra Leligdowicz, XiaoNing Xu, Mina John, Masafumi Takiguchi, Andrew McMichael, Sarah Rowland-Jones, and Tao Dong. Multilayered Defense in HLA-B51-Associated HIV Viral Control. J. Immunol., 187(2):684-691, 15 Jul 2011. PubMed ID: 21670313. Show all entries for this paper.


Displaying record number 52593

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Species (MHC/HLA) human(B51)
Immunogen  
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52641

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37 B)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Patient MHC/HLA A*0201, A*2501, B18, B51, Cw*0102, Cw*1203
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 53787

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EL9
Species (MHC/HLA) (B51)
Immunogen  
Experimental methods  
Keywords review, immunodominance, escape, acute/early infection, early-expressed proteins, kinetics, viral fitness and reversion

Notes

References

Lichterfeld2005 Mathias Lichterfeld, Xu G. Yu, Sylvie Le Gall, and Marcus Altfeld. Immunodominance of HIV-1-Specific CD8+ T-Cell Responses in Acute HIV-1 Infection: At the Crossroads of Viral and Host Genetics. Trends Immunol., 26(3):166-171, Mar 2005. PubMed ID: 15745859. Show all entries for this paper.


Displaying record number 54372

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name B51-EI9(Vpr)
Species (MHC/HLA) human(B51)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 54155

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37 2001 HIV-1 subtype B cons)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Show epitope variants
Epitope Name EI9
Subtype B
Species (MHC/HLA) human(B*5101)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, mutation acquisition, optimal epitope

Notes

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


Displaying record number 58147

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Show epitope variants
Epitope Name EI9
Subtype B
Species (MHC/HLA) human(B*5101)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords escape, acute/early infection

Notes

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


Displaying record number 59086

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*5101)
Immunogen HIV-1 infection
Patient MHC/HLA PIC1362: A*0201, A*2501, B*1801, B*5101, Cw*0102, Cw*1203
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion

Notes

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59589

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(B*81)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59594

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9
Species (MHC/HLA) human(C*06)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56451

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Epitope Name EI9(Vpr)
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords non-susceptible form

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55797

HXB2 Location Vpr(29-37)
DNA(5643..5669)
Vpr Epitope Map
Author Location Vpr(29-37)
Epitope EAVRHFPRI Epitope Alignment
EAVRHFPRI epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords computational epitope prediction, HLA associated polymorphism

Notes

References

Srinivasan2008 Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S. Kalyanaraman, Anthony Cristillo, Ronald G. Collman, Nelly Morellet, Bassel E. Sawaya, and Ramachandran Murali. A Comprehensive Analysis of the Naturally Occurring Polymorphisms in HIV-1 Vpr: Potential Impact on CTL Epitopes. Virol. J., 5:99, 2008. PubMed ID: 18721481. Show all entries for this paper.


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