HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 53572

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location Pol(87-95)
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Subtype B
Species (MHC/HLA) human(A28)
Immunogen HIV-1 infection
Patient MHC/HLA A28, A29, B14, B44, Cw8
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 53385

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location ( B consensus)
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Epitope Name DL9
Subtype B
Species (MHC/HLA) human(A68)
Immunogen HIV-1 infection
Patient MHC/HLA A31, A68, B7, B70, Cw1, Cw7
Country United States
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 55029

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location  
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Species (MHC/HLA) human(A68)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 398

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location Pol( subtype B)
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords subtype comparisons

Notes

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 57331

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location Pol
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Subtype A, CRF02_AG, CRF06_cpx, CRF09_cpx
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Country Burkina Faso
Experimental methods Other
Keywords drug resistance

Notes

References

Tebit2009 Denis M. Tebit, Lassana Sangaré, Fabrice Tiba, Yameogo Saydou, Aline Makamtse, Hermann Somlare, Guillaume Bado, Boris G. Kouldiaty, Inoussa Zabsonre, Sibiri L. Yameogo, Kanokporn Sathiandee, Joseph Y. Drabo, and Hans-Georg Kräusslich. Analysis of the Diversity of the HIV-1 pol Gene and Drug Resistance Associated Changes among Drug-Naïve Patients in Burkina Faso. J. Med. Virol., 81(10):1691-701, Oct 2009. PubMed ID: 19697403. Show all entries for this paper.


Displaying record number 59576

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HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location Pol(86-94)
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Epitope Name DL9
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61261

Download this epitope record as JSON.

HXB2 Location Pol(86-94)
Protease(30-38)
DNA(2340..2366)
Pol Epitope Map
Author Location Protease
Epitope DTVLEEMNL Epitope Alignment
DTVLEEMNL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Mexico, Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords drug resistance

Notes

References

Blanco-Heredia2016 Juan Blanco-Heredia, Aarón Lecanda, Humberto Valenzuela-Ponce, Christian Brander, Santiago Ávila-Rios, and Gustavo Reyes-Terán. Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naive HIV-Infected Individuals. PLoS One, 11(1):e0147571, 2016. PubMed ID: 26808823. Show all entries for this paper.


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